Synthesis, conformation and biological evaluation of the enantiomers of 3-fluoro-gamma-aminobutyric acid ((R)- and (S)-3F-GABA): An analogue of the neurotransmitter GABA

Keyphrases

• Neurotransmitters 100%
• γ-aminobutyric Acid 100%
• Synthetic Evaluation 100%
• Biological Evaluation 100%
• Fluoro 100%
• GABAA Receptor (GABAAR) 50%
• Xenopus Laevis 50%
• Whole Animal 50%
• Tadpole 50%
• Central Nervous System 50%
• Aqueous Solution 50%
• B3LYP 50%
• Inhibitory Amino Acids 50%
• Amino Acid Neurotransmitters 50%
• Preferred Conformation 50%
• NMR Coupling Constants 50%
• NMR Spectra 50%
• Continuum Solvent Model 50%
• First Synthesis 50%
• Solution Conformation 50%
• DFT Calculations 50%

Agricultural and Biological Sciences

• Neurotransmitter 100%
• Gamma-Aminobutyric Acid 100%
• Amino Acid 50%
• Agonist 50%
• Xenopus laevis 50%
• Tadpole 50%
• Central Nervous System 50%
• Aqueous Solution 50%

Immunology and Microbiology

• Conformation 100%
• Enantiomer 100%
• Solution and Solubility 33%
• Xenopus laevis 33%
• Agonist 33%
• Aqueous Solution 33%
• Central Nervous System 33%
• Tadpole 33%
• Coupling Constant 33%