Synthesis of 3 '-, 4 '- and 6 '-deoxy and other analogues of D-glucosaminylphosphatidylinositol

Charles N.  Borissow; Terry K.  Smith; Michael A. J.  Ferguson; John S.  Brimacombe

doi:10.1016/S0040-4039(00)01901-8

Synthesis of 3 '-, 4 '- and 6 '-deoxy and other analogues of D-glucosaminylphosphatidylinositol

Charles N. Borissow, Terry K. Smith, Michael A. J. Ferguson, John S. Brimacombe

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Abstract

Deoxy and other analogues of D-glucosaminylphosphatidylinositol 1 have been synthesised and tested as substrates or inhibitors of a de-N-acetylase and mannosyltransferase (MT-1) involved in the biosynthesis of the glycosylphosphatidylinositol (GPI) membrane anchor of the parasite Trypanosoma brucei. (C) 2000 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	121-123
Number of pages	3
Journal	Tetrahedron Letters
Volume	42
Issue number	1
DOIs	https://doi.org/10.1016/S0040-4039(00)01901-8
Publication status	Published - 1 Jan 2001

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title = "Synthesis of 3 '-, 4 '- and 6 '-deoxy and other analogues of D-glucosaminylphosphatidylinositol",

abstract = "Deoxy and other analogues of D-glucosaminylphosphatidylinositol 1 have been synthesised and tested as substrates or inhibitors of a de-N-acetylase and mannosyltransferase (MT-1) involved in the biosynthesis of the glycosylphosphatidylinositol (GPI) membrane anchor of the parasite Trypanosoma brucei. (C) 2000 Elsevier Science Ltd. All rights reserved.",

author = "Borissow, {Charles N.} and Smith, {Terry K.} and Ferguson, {Michael A. J.} and Brimacombe, {John S.}",

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T1 - Synthesis of 3 '-, 4 '- and 6 '-deoxy and other analogues of D-glucosaminylphosphatidylinositol

AU - Borissow, Charles N.

AU - Smith, Terry K.

AU - Ferguson, Michael A. J.

AU - Brimacombe, John S.

PY - 2001/1/1

Y1 - 2001/1/1

N2 - Deoxy and other analogues of D-glucosaminylphosphatidylinositol 1 have been synthesised and tested as substrates or inhibitors of a de-N-acetylase and mannosyltransferase (MT-1) involved in the biosynthesis of the glycosylphosphatidylinositol (GPI) membrane anchor of the parasite Trypanosoma brucei. (C) 2000 Elsevier Science Ltd. All rights reserved.

AB - Deoxy and other analogues of D-glucosaminylphosphatidylinositol 1 have been synthesised and tested as substrates or inhibitors of a de-N-acetylase and mannosyltransferase (MT-1) involved in the biosynthesis of the glycosylphosphatidylinositol (GPI) membrane anchor of the parasite Trypanosoma brucei. (C) 2000 Elsevier Science Ltd. All rights reserved.

U2 - 10.1016/S0040-4039(00)01901-8

DO - 10.1016/S0040-4039(00)01901-8

M3 - Article

SN - 0040-4039

VL - 42

SP - 121

EP - 123

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 1

ER -

Synthesis of 3 '-, 4 '- and 6 '-deoxy and other analogues of D-glucosaminylphosphatidylinositol

Abstract

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