Abstract
6-N-Biotinylaminohexyl isopropyl phosphorofluoridate 2 was prepared by treatment of the corresponding hydrogen phosphonic diester with triethylamine trihydrofluoride and iodine. The activity of the phosphorofluoridate was tested by the inhibition of a-chymotrypsin.
Original language | English |
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Pages (from-to) | 407-409 |
Number of pages | 3 |
Journal | Synthesis-Stuttgart |
Issue number | 3 |
DOIs | |
Publication status | Published - Mar 1999 |
Keywords
- Biotinylated analogue of diisopropylfluorophosphate
- 6-N-biotinylaminohexanol
- H-phosphonate condensation
- Halide exchange
- Biotin