Synthesis of a homochiral α,α-disubstituted α,β-diamino-acid

Raymond C. F. Jolles, Alan K. Crockett, David C. Rees, Ian Gilbert

    Research output: Contribution to journalComment/debatepeer-review

    21 Citations (Scopus)


    The synthesis at a homochiral a,a-disubstituted a,ß-amino-acid is described from norleucine using stereospecific alkylation of a homochiral oxazolidinone enolate; an optically active pseudotetrapeptide analogue of CCK-4 is prepared to show an application of such diamino-acids.

    Original languageEnglish
    Pages (from-to)1661-1664
    Number of pages4
    JournalTetrahedron: Asymmetry
    Issue number9
    Publication statusPublished - 1994


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