Abstract
An isosteric C-glycoside phosphono analogue of dec-9-enyl beta -D-galactopyranosyl-(1 -->4)-alpha -D-mannopyranosyl phosphate was synthesised and showed high biological activity in the Leishmania MPT assay. A one-step Horner-Emmons/Michael reaction was developed for the stereoselective preparation of cc-D-mannosyl methanephosphonate derivatives. (C) 2001 Elsevier Science Ltd. All rights reserved.
Original language | English |
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Pages (from-to) | 5305-5308 |
Number of pages | 4 |
Journal | Tetrahedron Letters |
Volume | 42 |
Issue number | 31 |
DOIs | |
Publication status | Published - 30 Jul 2001 |