Synthetic biology of B cell activation: understanding signal amplification at the B cell antigen receptor using a rebuilding approach

Keyphrases

• Immunoreceptor Tyrosine-based Activation Motif 100%
• B Cell Receptor 100%
• B Cell Activation 100%
• Signal Amplification 100%
• Synthetic Biology 100%
• Spleen Tyrosine Kinase 75%
• Tyrosine 62%
• Phosphorylation 25%
• Leucine 25%
• Glycine 25%
• Binding Site 12%
• Kinase Activation 12%
• Downstream Signaling 12%
• Initiation Complex 12%
• Src Kinase 12%
• Transphosphorylation 12%
• SH2 Domain 12%
• Signaling Elements 12%
• In Cis 12%
• Reconstitution Experiments 12%
• Preactivated 12%
• Y(III) 12%

Biochemistry, Genetics and Molecular Biology

• Cell Activation 100%
• B Cell 100%
• Immunoreceptor Tyrosine-Based Activation Motif 100%
• Janus Kinase 1 75%
• Tyrosine 62%
• Intravenous Immunoglobulin 50%
• Leucine 25%
• Binding Site 12%
• Initiation Complex 12%
• SH2 Domain 12%
• Src Family Kinase 12%
• Reconstitution Experiment 12%

Immunology and Microbiology

• B Cell 100%
• Cell Antigen 100%
• B Cell Activation 100%
• Tyrosine 100%
• Immunoreceptor Tyrosine-Based Activation Motif 72%
• Intravenous Immunoglobulin 36%
• Leucine 18%
• Binding Site 9%