Abstract
The phosphorylated branched heptasaccharides 7 and 8, the octasaccharide 9 and the phosphorylated trisaccharides 5 and 6, which are fragments of the phosphoglycan portion of the lipophosphoglycans from Leishmania mexicana (5) or L. major (6–9), were synthesised by using the hydrogenphosphonate method for the preparation of phosphodiester bridges. The compounds were tested as acceptor substrates/putative inhibitors for the Leishmania elongating -D-mannosylphosphate transferase.
Original language | English |
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Pages (from-to) | 2019-2030 |
Number of pages | 12 |
Journal | Chemistry: a European Journal |
Volume | 11 |
Issue number | 7 |
DOIs | |
Publication status | Published - 2005 |