Systematic Review of Clinical Practice Guidelines for Oral Health in Children With Cleft Lip and Palate

Ankita Saikia, M. S. Muthu (Lead / Corresponding author), Omolola O. Orenuga, Peter Mossey, Lahcen Ousehal, Si Yan, Marina Campodonico, Rachael England, Sean Taylor, Pamela Sheeran

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)
189 Downloads (Pure)


Objective: Clinical practice guidelines (CPGs) exist to present recommendations and policies aimed at optimizing the oral health of children and adolescents born with cleft lip and/or palate. The aim of this review is to identify and assess the scope, quality, adequacy, and consistency of CPGs related to oral health in children and adolescents with clefts, along with reporting any differences and shortcomings.

Methods: A systematic review of the literature of CPGs following Preferred Reporting Items for Systematic Reviews guidelines was conducted. Assessment of selected CPGs was performed using the Appraisal of Guidelines for Research & Evaluation II methodological quality instrument.

Results: Only 7 CPGs fulfilled the criteria. Of these, 4 were from the American Cleft Palate-Craniofacial Association, and 1 each from the American Academy of Pediatrics, the Academy of Breastfeeding Medicine, and the American Academy of Pediatric Dentistry. The lowest overall mean scores were in the domain “Rigor of Development” (mean 29.58%, SD 17.11), revealing lower quality in methodology of the guideline. The domain “Clarity of Presentation” (mean 73.80%, SD 7.87) revealed the best score.

Conclusions: Our review results reveal a lack of integrated high-quality CPGs that can be used as universal guidelines by health workers in a range of disciplines for improving oral health in children and adolescents with cleft problems.
Original languageEnglish
Pages (from-to)800-814
Number of pages15
JournalCleft Palate-Craniofacial Journal
Issue number6
Early online date23 Jun 2021
Publication statusPublished - Jun 2022


  • cleft
  • children
  • guideline
  • oral health
  • systematic review
  • Oral Surgery
  • Otorhinolaryngology

ASJC Scopus subject areas

  • Oral Surgery
  • Otorhinolaryngology


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