Tablet: visualizing next-generation sequence assemblies and mappings

Iain Milne (Lead / Corresponding author), Micha Bayer, Gordon Stephen, Linda Cardle, David Marshall

Research output: Chapter in Book/Report/Conference proceedingChapter (peer-reviewed)peer-review

18 Citations (Scopus)

Abstract

This chapter is designed to be a practical guide to using Tablet for the visualization of next/second-generation (NGS) sequencing data. NGS data is being produced more frequently and in greater data volumes every year. As such, it is increasingly important to have tools which enable biologists and bioinformaticians to understand and gain key insights into their data. Visualization can play a key role in the exploration of such data as well as aid in the visual validation of sequence assemblies and features such as single nucleotide polymorphisms (SNPs). We aim to show several use cases which demonstrate Tablet's ability to visually highlight various situations of interest which can arise in NGS data.

Original languageEnglish
Title of host publicationPlant bioinformatics
Subtitle of host publicationmethods and protocols
EditorsDavid Edwards
Place of PublicationNew York
PublisherSpringer
Pages253-268
Number of pages16
ISBN (Electronic)9781493931675
ISBN (Print)9781493931668
DOIs
Publication statusPublished - 2016

Publication series

NameMethods in molecular biology
PublisherSpringer
Volume1374
ISSN (Print)1064-3745

Keywords

  • Chromosome mapping
  • Computational biology
  • Genomics
  • High-throughput nucleotide Sequencing
  • Sequence analysis, DNA
  • Software
  • Web browser

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