Temporal glucose metabolism in borderline personality disorder

JoséManuel De la Fuente, Françoise Lotstra, Serge Goldman, Françoise Biver, André Luxen, Luc Bidaut, Etienne Stanus, Julien Mendlewicz

    Research output: Contribution to journalArticlepeer-review

    25 Citations (Scopus)


    The pathophysiology of borderline personality disorder (BPD) is obscure. Underlying organic factors such as epilepsy are suspected because clinical characteristics of the syndrome are similar to some manifestations of patients with complex partial seizures (CPS). Positron emission tomography (PET) with F-fluorodeoxyglucose (FDG) reveals hypometabolism in the area surrounding epileptic foci. To test the epilepsy hypothesis in BPD, we have explored 10 patients with BPD and compared them with 15 control subjects using PET with FDG. We conclude that PET provides no metabolic indication of temporal lobe epilepsy in BPD.
    Original languageEnglish
    Pages (from-to)237-245
    Number of pages9
    JournalPsychiatry Research: Neuroimaging
    Issue number4
    Publication statusPublished - Dec 1994


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