The 12-Item Hypoglycemia Impact Profile (HIP12): psychometric validation of a brief measure of the impact of hypoglycemia on quality of life among adults with type 1 or type 2 diabetes

TY - JOUR

T1 - The 12-Item Hypoglycemia Impact Profile (HIP12)

T2 - psychometric validation of a brief measure of the impact of hypoglycemia on quality of life among adults with type 1 or type 2 diabetes

AU - Hypo-RESOLVE Consortium

AU - Broadley, Melanie

AU - Chatwin, Hannah

AU - Søholm, Uffe

AU - Amiel, Stephanie A.

AU - Carlton, Jill

AU - De Galan, Bastiaan E.

AU - Hendrieckx, Christel

AU - McCrimmon, Rory J.

AU - Skovlund, Søren E.

AU - Pouwer, Frans

AU - Speight, Jane

N1 - Funding Information: This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (JU) under grant agreement number 777460. The JU receives support from the European Union’s Horizon 2020 research and innovation program and the EFPIA and T1D Exchange, JDRF, International Diabetes Federation (IDF), and The Leona M and Harry B Helmsley Charitable Trust. CH and JS are supported by core funding to the Australian Centre for Behavioural Research in Diabetes provided by the collaboration between Diabetes Victoria and Deakin University Funding Information: © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

PY - 2022/8/17

Y1 - 2022/8/17

N2 - Introduction The aim of this study was to determine the psychometric properties of the 12-Item Hypoglycemia Impact Profile (HIP12), a brief measure of the impact of hypoglycemia on quality of life (QoL) among adults with type 1 (T1D) or type 2 diabetes (T2D). Research design and methods Adults with T1D (n=1071) or T2D (n=194) participating in the multicountry, online study, â € Your SAY: Hypoglycemia', completed the HIP12. Psychometric analyses were undertaken to determine acceptability, structural validity, internal consistency, convergent/divergent validity, and known-groups validity. Results Most (98%) participants completed all items on the HIP12. The expected one-factor solution was supported for T1D, T2D, native English speaker, and non-native English speaker groups. Internal consistency was high across all groups (ω=0.91-0.93). Convergent and divergent validity were satisfactory. Known-groups validity was demonstrated for both diabetes types, by frequency of severe hypoglycemia (0 vs ≥1 episode in the past 12 months) and self-treated episodes (<2 vs 2-4 vs ≥5 per week). The measure also discriminated by awareness of hypoglycemia in those with T1D. Conclusions The HIP12 is an acceptable, internally consistent, and valid tool for assessing the impact of hypoglycemia on QoL among adults with T1D. The findings in the relatively small sample with T2D are encouraging and warrant replication in a larger sample.

AB - Introduction The aim of this study was to determine the psychometric properties of the 12-Item Hypoglycemia Impact Profile (HIP12), a brief measure of the impact of hypoglycemia on quality of life (QoL) among adults with type 1 (T1D) or type 2 diabetes (T2D). Research design and methods Adults with T1D (n=1071) or T2D (n=194) participating in the multicountry, online study, â € Your SAY: Hypoglycemia', completed the HIP12. Psychometric analyses were undertaken to determine acceptability, structural validity, internal consistency, convergent/divergent validity, and known-groups validity. Results Most (98%) participants completed all items on the HIP12. The expected one-factor solution was supported for T1D, T2D, native English speaker, and non-native English speaker groups. Internal consistency was high across all groups (ω=0.91-0.93). Convergent and divergent validity were satisfactory. Known-groups validity was demonstrated for both diabetes types, by frequency of severe hypoglycemia (0 vs ≥1 episode in the past 12 months) and self-treated episodes (<2 vs 2-4 vs ≥5 per week). The measure also discriminated by awareness of hypoglycemia in those with T1D. Conclusions The HIP12 is an acceptable, internally consistent, and valid tool for assessing the impact of hypoglycemia on QoL among adults with T1D. The findings in the relatively small sample with T2D are encouraging and warrant replication in a larger sample.

KW - Adult

KW - Diabetes Mellitus, Type 1

KW - Diabetes Mellitus, Type 2

KW - Humans

KW - Hypoglycemia

KW - Psychometrics

KW - Quality of Life

KW - hypoglycemia

KW - psychometrics

KW - psychosocial issues

KW - quality of life

KW - Psychosocial issuesc

KW - Quality of life

UR - https://www.scopus.com/pages/publications/85136059263

U2 - 10.1136/bmjdrc-2022-002890

DO - 10.1136/bmjdrc-2022-002890

M3 - Article

C2 - 35977753

SN - 2052-4897

VL - 10

JO - BMJ Open Diabetes Research and Care

JF - BMJ Open Diabetes Research and Care

IS - 4

M1 - e002890

ER -