TY - JOUR
T1 - The amino acid sequence of rabbit skeletal muscle glycogenin
AU - Campbell, David G.
AU - Cohen, Philip
PY - 1989/10
Y1 - 1989/10
N2 - The amino acid sequence of glycogenin from rabbit skeletal muscle has been determined. The N‐acetylated protein consists of 332 amino acids and has a molecular mass of 37278 Da. The novel tyrosyl‐glucose linkage between glycogenin and glycogen [Smythe, C., Caudwell, F. B., Ferguson, M. & Cohen, P. (1988) EMBO J. 7, 2681–2686] is shown to occur at a single site, tyrosine‐194. Although glycogenin is a UDP‐Glc utilising glucosyltransferase that self‐glucosylates [Pitcher, J., Smythe, C. & Cohen, P. (1988) Eur. J. Biochem. 176, 391–395], following addition by an unknown enzyme of the first glucose to tyrosine‐194, it is not homologous to either human glycogen synthase or other UDP‐Glc‐requiring enzymes.
AB - The amino acid sequence of glycogenin from rabbit skeletal muscle has been determined. The N‐acetylated protein consists of 332 amino acids and has a molecular mass of 37278 Da. The novel tyrosyl‐glucose linkage between glycogenin and glycogen [Smythe, C., Caudwell, F. B., Ferguson, M. & Cohen, P. (1988) EMBO J. 7, 2681–2686] is shown to occur at a single site, tyrosine‐194. Although glycogenin is a UDP‐Glc utilising glucosyltransferase that self‐glucosylates [Pitcher, J., Smythe, C. & Cohen, P. (1988) Eur. J. Biochem. 176, 391–395], following addition by an unknown enzyme of the first glucose to tyrosine‐194, it is not homologous to either human glycogen synthase or other UDP‐Glc‐requiring enzymes.
UR - http://www.scopus.com/inward/record.url?scp=0024424199&partnerID=8YFLogxK
U2 - 10.1111/j.1432-1033.1989.tb15090.x
DO - 10.1111/j.1432-1033.1989.tb15090.x
M3 - Article
C2 - 2806254
AN - SCOPUS:0024424199
SN - 0014-2956
VL - 185
SP - 119
EP - 125
JO - European Journal of Biochemistry
JF - European Journal of Biochemistry
IS - 1
ER -