The amino acid sequence of rabbit skeletal muscle glycogenin

TY - JOUR

T1 - The amino acid sequence of rabbit skeletal muscle glycogenin

AU - Campbell, David G.

AU - Cohen, Philip

PY - 1989/10

Y1 - 1989/10

N2 - The amino acid sequence of glycogenin from rabbit skeletal muscle has been determined. The N‐acetylated protein consists of 332 amino acids and has a molecular mass of 37278 Da. The novel tyrosyl‐glucose linkage between glycogenin and glycogen [Smythe, C., Caudwell, F. B., Ferguson, M. & Cohen, P. (1988) EMBO J. 7, 2681–2686] is shown to occur at a single site, tyrosine‐194. Although glycogenin is a UDP‐Glc utilising glucosyltransferase that self‐glucosylates [Pitcher, J., Smythe, C. & Cohen, P. (1988) Eur. J. Biochem. 176, 391–395], following addition by an unknown enzyme of the first glucose to tyrosine‐194, it is not homologous to either human glycogen synthase or other UDP‐Glc‐requiring enzymes.

AB - The amino acid sequence of glycogenin from rabbit skeletal muscle has been determined. The N‐acetylated protein consists of 332 amino acids and has a molecular mass of 37278 Da. The novel tyrosyl‐glucose linkage between glycogenin and glycogen [Smythe, C., Caudwell, F. B., Ferguson, M. & Cohen, P. (1988) EMBO J. 7, 2681–2686] is shown to occur at a single site, tyrosine‐194. Although glycogenin is a UDP‐Glc utilising glucosyltransferase that self‐glucosylates [Pitcher, J., Smythe, C. & Cohen, P. (1988) Eur. J. Biochem. 176, 391–395], following addition by an unknown enzyme of the first glucose to tyrosine‐194, it is not homologous to either human glycogen synthase or other UDP‐Glc‐requiring enzymes.

UR - https://www.scopus.com/pages/publications/0024424199

U2 - 10.1111/j.1432-1033.1989.tb15090.x

DO - 10.1111/j.1432-1033.1989.tb15090.x

M3 - Article

C2 - 2806254

AN - SCOPUS:0024424199

SN - 0014-2956

VL - 185

SP - 119

EP - 125

JO - European Journal of Biochemistry

JF - European Journal of Biochemistry

IS - 1

ER -