The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K+ channels in the rat insulinoma cell line, CRI-G1

Jackie M Kinsella, Hilary A Laidlaw, Teresa Tang, Jenni Harvey, Calum Sutherland, Michael L J Ashford

    Research output: Contribution to journalArticlepeer-review

    3 Citations (Scopus)

    Abstract

    3-guanidinopropionic acid derivatives reduce body weight in obese, diabetic mice. We have assessed whether one of these analogues, the aminoguanidine carboxylate BVT.12777, opens KATP channels in rat insulinoma cells, by the same mechanism as leptin.

    Original languageEnglish
    Number of pages13
    JournalBMC Clinical Pharmacology
    Volume4
    Issue number17
    DOIs
    Publication statusPublished - 2004

    Fingerprint Dive into the research topics of 'The aminoguanidine carboxylate BVT.12777 activates ATP-sensitive K<sup>+</sup> channels in the rat insulinoma cell line, CRI-G1'. Together they form a unique fingerprint.

    Cite this