The Arabidopsis epitranscriptome

Rupert G. Fray; Gordon G. Simpson

doi:10.1016/j.pbi.2015.05.015

The Arabidopsis epitranscriptome

Rupert G. Fray (Lead / Corresponding author), Gordon G. Simpson (Lead / Corresponding author)

Plant Sciences

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34 Citations (Scopus)

220 Downloads (Pure)

Abstract

The most prevalent internal modification of plant messenger RNAs, N<sup>6</sup>-methyladenosine (m<sup>6</sup>A), was first discovered in the 1970s, then largely forgotten. However, the impact of modifications to eukaryote mRNA, collectively known as the epitranscriptome, has recently attracted renewed attention. mRNA methylation is required for normal Arabidopsis development and the first methylation maps reveal that thousands of Arabidopsis mRNAs are methylated. Arabidopsis is likely to be a model of wide utility in understanding the biological impacts of the epitranscriptome. We review recent progress and look ahead with questions awaiting answers to reveal an entire layer of gene regulation that has until recently been overlooked.

Original language	English
Pages (from-to)	17-21
Number of pages	5
Journal	Current Opinion in Plant Biology
Volume	27
Early online date	3 Jun 2015
DOIs	https://doi.org/10.1016/j.pbi.2015.05.015
Publication status	Published - Oct 2015

ASJC Scopus subject areas

Plant Science

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10.1016/j.pbi.2015.05.015Licence: CC BY

Publisher final verison
© 2015 The Authors. Published by Elsevier Ltd. This is an open access article under the CCBY license (http://creativecommons.org/licenses/by/4.0/
Final published version, 420 KBLicence: CC BY

Cite this

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The Arabidopsis epitranscriptome

Abstract

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Diversifying Transcription Termination Function