TY - JOUR
T1 - The beneficial effects of omega-3 and omega-6 essential fatty acid supplementation on red blood cell rheology
AU - Ho, M.
AU - Maple, C.
AU - Bancroft, A.
AU - McLaren, M.
AU - Belch, J. J. F.
PY - 1999
Y1 - 1999
N2 - Twenty healthy, non-smoking subjects were enrolled into a study to investigate the effects of dietary supplementation with essential fatty acid (EFAs) on red blood cell rheology. Ten subjects were given 3 months dietary supplementation with long chain polyunsaturated EFAs containing omega-3 and omega-6 EFAs while 10 others were given placebo (sunflower oil). Venous sampling was performed at 0 and 12 weeks and red blood cell (RBC) aggregation and deformability measured by a filtration system. The results showed a reduction in RBC aggregation in the group given omega-3 and omega-6 EFAs but not in the placebo group. This may be related to changes in the RBC membrane and surface receptor characteristics. Such EFAs may be useful in Raynaud's phenomenon.
AB - Twenty healthy, non-smoking subjects were enrolled into a study to investigate the effects of dietary supplementation with essential fatty acid (EFAs) on red blood cell rheology. Ten subjects were given 3 months dietary supplementation with long chain polyunsaturated EFAs containing omega-3 and omega-6 EFAs while 10 others were given placebo (sunflower oil). Venous sampling was performed at 0 and 12 weeks and red blood cell (RBC) aggregation and deformability measured by a filtration system. The results showed a reduction in RBC aggregation in the group given omega-3 and omega-6 EFAs but not in the placebo group. This may be related to changes in the RBC membrane and surface receptor characteristics. Such EFAs may be useful in Raynaud's phenomenon.
U2 - 10.1054/plef.1999.0066
DO - 10.1054/plef.1999.0066
M3 - Article
C2 - 10477036
SN - 0952-3278
VL - 61
SP - 13
EP - 17
JO - Prostaglandins, Leukotrienes, and Essential Fatty Acids
JF - Prostaglandins, Leukotrienes, and Essential Fatty Acids
IS - 1
ER -