The cell biology of late blight disease

Stephen C. Whisson, Petra C. Boevink, Shumei Wang, Paul R. J. Birch (Lead / Corresponding author)

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Abstract

Late blight, caused by the oomycete Phytophthora infestans, is a major global disease of potato and tomato. Cell biology is teaching us much about the developmental stages associated with infection, especially the haustorium, which is a site of intimate interaction and molecular exchange between pathogen and host. Recent observations suggest a role for the plant endocytic cycle in specific recruitment of host proteins to the Extra-Haustorial Membrane, emphasising the unique nature of this membrane compartment. In addition, there has been a strong focus on the activities of RXLR effectors, which are delivered into plant cells to modulate and manipulate host processes. RXLR effectors interact directly with diverse plant proteins at a range of subcellular locations to promote disease.
Original languageEnglish
Pages (from-to)127-135
Number of pages9
JournalCurrent Opinion in Microbiology
Volume34
Early online date7 Oct 2016
DOIs
Publication statusPublished - Dec 2016

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Cell Biology
Phytophthora infestans
Oomycetes
Plant Proteins
Membranes
Plant Cells
Lycopersicon esculentum
Solanum tuberosum
Teaching
Infection
Proteins

Cite this

Whisson, Stephen C. ; Boevink, Petra C. ; Wang, Shumei ; Birch, Paul R. J. / The cell biology of late blight disease. In: Current Opinion in Microbiology. 2016 ; Vol. 34. pp. 127-135.
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The cell biology of late blight disease. / Whisson, Stephen C.; Boevink, Petra C.; Wang, Shumei; Birch, Paul R. J. (Lead / Corresponding author).

In: Current Opinion in Microbiology, Vol. 34, 12.2016, p. 127-135.

Research output: Contribution to journalArticle

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