The cell biology of late blight disease

Stephen C. Whisson, Petra C. Boevink, Shumei Wang, Paul R. J. Birch (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

94 Citations (Scopus)
255 Downloads (Pure)


Late blight, caused by the oomycete Phytophthora infestans, is a major global disease of potato and tomato. Cell biology is teaching us much about the developmental stages associated with infection, especially the haustorium, which is a site of intimate interaction and molecular exchange between pathogen and host. Recent observations suggest a role for the plant endocytic cycle in specific recruitment of host proteins to the Extra-Haustorial Membrane, emphasising the unique nature of this membrane compartment. In addition, there has been a strong focus on the activities of RXLR effectors, which are delivered into plant cells to modulate and manipulate host processes. RXLR effectors interact directly with diverse plant proteins at a range of subcellular locations to promote disease.
Original languageEnglish
Pages (from-to)127-135
Number of pages9
JournalCurrent Opinion in Microbiology
Early online date7 Oct 2016
Publication statusPublished - Dec 2016


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