The cell biology of late blight disease

Stephen C. Whisson, Petra C. Boevink, Shumei Wang, Paul R. J. Birch (Lead / Corresponding author)

Research output: Contribution to journalArticle

43 Citations (Scopus)
208 Downloads (Pure)


Late blight, caused by the oomycete Phytophthora infestans, is a major global disease of potato and tomato. Cell biology is teaching us much about the developmental stages associated with infection, especially the haustorium, which is a site of intimate interaction and molecular exchange between pathogen and host. Recent observations suggest a role for the plant endocytic cycle in specific recruitment of host proteins to the Extra-Haustorial Membrane, emphasising the unique nature of this membrane compartment. In addition, there has been a strong focus on the activities of RXLR effectors, which are delivered into plant cells to modulate and manipulate host processes. RXLR effectors interact directly with diverse plant proteins at a range of subcellular locations to promote disease.
Original languageEnglish
Pages (from-to)127-135
Number of pages9
JournalCurrent Opinion in Microbiology
Early online date7 Oct 2016
Publication statusPublished - Dec 2016

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  • Projects

    Student Theses

    Secretion and delivery of virulence proteins from Phytophthora infestans to its host

    Author: Wang, S., 2019

    Supervisor: Birch, P. (Supervisor), Boevink, P. (Supervisor) & Whisson, S. (Supervisor)

    Student thesis: Doctoral ThesisDoctor of Philosophy

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