The chirality of a four-way helical junction in RNA

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    Abstract

    We have used a novel electrophoretic approach to determine the chirality of a four-way helical junction in RNA. From our experiments we conclude that the handedness of the helical junction in the complete ribozyme is opposite to that found in the free junction and is therefore constrained by the interaction between the unpaired loops of the ribozyme.
    Original languageEnglish
    Pages (from-to)4126-4127
    Number of pages2
    JournalJournal of the American Chemical Society
    Volume126
    Issue number13
    DOIs
    Publication statusPublished - Mar 2004

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