The coiled body

Angus I. Lamond, Maria Carmo-Fonseca

Research output: Contribution to journalArticlepeer-review

159 Citations (Scopus)


The coiled body is a nuclear organelle that contains snRNPs involved in splicing, the non-snRNP splicing factor U2AF and the nucleolar protein fibrillarin. It is highly conserved in evolution and is present in both animal and plant cells. The coiled body is a dynamic structure that can undergo regulated cycles of assembly and disassembly during interphase and mitosis and it may represent a distinct metabolic compartment within the nucleus.

Original languageEnglish
Pages (from-to)198-203
Number of pages6
JournalTrends in Cell Biology
Issue number6
Publication statusPublished - Jun 1993


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