The coiled body

Angus I. Lamond, Maria Carmo-Fonseca

    Research output: Contribution to journalArticlepeer-review

    160 Citations (Scopus)


    The coiled body is a nuclear organelle that contains snRNPs involved in splicing, the non-snRNP splicing factor U2AF and the nucleolar protein fibrillarin. It is highly conserved in evolution and is present in both animal and plant cells. The coiled body is a dynamic structure that can undergo regulated cycles of assembly and disassembly during interphase and mitosis and it may represent a distinct metabolic compartment within the nucleus.

    Original languageEnglish
    Pages (from-to)198-203
    Number of pages6
    JournalTrends in Cell Biology
    Issue number6
    Publication statusPublished - Jun 1993

    ASJC Scopus subject areas

    • Cell Biology


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