The concise guide to PHARMACOLOGY 2013/14: Catalytic receptors

Stephen P.H. Alexander (Lead / Corresponding author), Helen E. Benson, Elena Faccenda, Adam J. Pawson, Joanna L. Sharman, Michael Spedding, John A. Peters, Anthony J. Harmar

    Research output: Contribution to journalArticle

    141 Citations (Scopus)

    Abstract

    The Concise Guide to PHARMACOLOGY 2013/14 provides concise overviews of the key properties of over 2000 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley. com/doi/10.1111/bph.12444/full. Catalytic receptors are one of the seven major pharmacological targets into which the Guide is divided, with the others being G protein-coupled receptors, ligand-gated ion channels, ion channels, nuclear hormone receptors, transporters and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. A new landscape format has easy to use tables comparing related targets. It is a condensed version of material contemporary to late 2013, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in previous Guides to Receptors and Channels. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and the Guide to Receptors and Channels, providing a permanent, citable, point-in-time record that will survive database updates.
    Original languageEnglish
    Pages (from-to)1676-1705
    Number of pages30
    JournalBritish Journal of Pharmacology
    Volume170
    Issue number8
    DOIs
    Publication statusPublished - 1 Dec 2013

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  • Cite this

    Alexander, S. P. H., Benson, H. E., Faccenda, E., Pawson, A. J., Sharman, J. L., Spedding, M., Peters, J. A., & Harmar, A. J. (2013). The concise guide to PHARMACOLOGY 2013/14: Catalytic receptors. British Journal of Pharmacology, 170(8), 1676-1705. https://doi.org/10.1111/bph.12449