The Concise Guide to PHARMACOLOGY 2015/16: Overview

Stephen P H Alexander, Eamonn Kelly, Neil Marrion, John A. Peters, Helen E. Benson, Elena Faccenda, Adam J. Pawson, Joanna L. Sharman, Christopher Southan, O. Peter Buneman, William A. Catterall, John A. Cidlowski, Anthony P. Davenport, Doriano Fabbro, Grace Fan, John C. McGrath, Michael Spedding, Jamie A. Davies

Research output: Contribution to journalArticlepeer-review

173 Citations (Scopus)
133 Downloads (Pure)

Abstract

The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.Wiley.com/doi/10.1111/bph.13347/full. This compilation of the major pharmacological targets is divided into eight areas of focus: G protein-coupled receptors, ligand-gated ion channels, voltage-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.

Original languageEnglish
Pages (from-to)5729-5743
Number of pages15
JournalBritish Journal of Pharmacology
Volume172
Issue number24
Early online date9 Dec 2015
DOIs
Publication statusPublished - Dec 2015

ASJC Scopus subject areas

  • Pharmacology

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