The Concise Guide to PHARMACOLOGY 2015/16

Voltage-gated ion channels

Stephen P. H. Alexander, William A. Catterall, Eamonn Kelly, Neil Marrion, John A. Peters, Helen E. Benson, Elena Faccenda, Adam J. Pawson, Joanna L. Sharman, Christopher Southan, Jamie A. Davies, and CGTP Collaborators

    Research output: Contribution to journalArticle

    160 Citations (Scopus)
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    Abstract

    The Concise Guide to PHARMACOLOGY 2015/16 provides concise overviews of the key properties of over 1750 human drug targets with their pharmacology, plus links to an open access knowledgebase of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. The full contents can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.13350/full. Voltage-gated ion channels are one of the eight major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ligand-gated ion channels, other ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The Concise Guide is published in landscape format in order to facilitate comparison of related targets. It is a condensed version of material contemporary to late 2015, which is presented in greater detail and constantly updated on the website www.guidetopharmacology.org, superseding data presented in the previous Guides to Receptors & Channels and the Concise Guide to PHARMACOLOGY 2013/14. It is produced in conjunction with NC-IUPHAR and provides the official IUPHAR classification and nomenclature for human drug targets, where appropriate. It consolidates information previously curated and displayed separately in IUPHAR-DB and GRAC and provides a permanent, citable, point-in-time record that will survive database updates.

    Original languageEnglish
    Pages (from-to)5904-5941
    Number of pages38
    JournalBritish Journal of Pharmacology
    Volume172
    Issue number24
    Early online date9 Dec 2015
    DOIs
    Publication statusPublished - Dec 2015

    Fingerprint

    Ion Channels
    Pharmacology
    Terminology
    Pharmaceutical Preparations
    Ligands
    Ligand-Gated Ion Channels
    Knowledge Bases
    Cytoplasmic and Nuclear Receptors
    G-Protein-Coupled Receptors
    Reading
    Databases
    Enzymes

    Keywords

    • Animals
    • Databases, Pharmaceutical
    • Humans
    • Ligands
    • Potassium channels, Voltage-Gated
    • Voltage-Gated Sodium Channels
    • Journal article

    Cite this

    Alexander, S. P. H., Catterall, W. A., Kelly, E., Marrion, N., Peters, J. A., Benson, H. E., ... and CGTP Collaborators (2015). The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels. British Journal of Pharmacology, 172(24), 5904-5941. https://doi.org/10.1111/bph.13349
    Alexander, Stephen P. H. ; Catterall, William A. ; Kelly, Eamonn ; Marrion, Neil ; Peters, John A. ; Benson, Helen E. ; Faccenda, Elena ; Pawson, Adam J. ; Sharman, Joanna L. ; Southan, Christopher ; Davies, Jamie A. ; and CGTP Collaborators. / The Concise Guide to PHARMACOLOGY 2015/16 : Voltage-gated ion channels. In: British Journal of Pharmacology. 2015 ; Vol. 172, No. 24. pp. 5904-5941.
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    Alexander, SPH, Catterall, WA, Kelly, E, Marrion, N, Peters, JA, Benson, HE, Faccenda, E, Pawson, AJ, Sharman, JL, Southan, C, Davies, JA & and CGTP Collaborators 2015, 'The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels', British Journal of Pharmacology, vol. 172, no. 24, pp. 5904-5941. https://doi.org/10.1111/bph.13349

    The Concise Guide to PHARMACOLOGY 2015/16 : Voltage-gated ion channels. / Alexander, Stephen P. H.; Catterall, William A.; Kelly, Eamonn; Marrion, Neil; Peters, John A.; Benson, Helen E.; Faccenda, Elena; Pawson, Adam J.; Sharman, Joanna L.; Southan, Christopher; Davies, Jamie A.; and CGTP Collaborators.

    In: British Journal of Pharmacology, Vol. 172, No. 24, 12.2015, p. 5904-5941.

    Research output: Contribution to journalArticle

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    AU - Benson, Helen E.

    AU - Faccenda, Elena

    AU - Pawson, Adam J.

    AU - Sharman, Joanna L.

    AU - Southan, Christopher

    AU - Davies, Jamie A.

    AU - and CGTP Collaborators

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    Alexander SPH, Catterall WA, Kelly E, Marrion N, Peters JA, Benson HE et al. The Concise Guide to PHARMACOLOGY 2015/16: Voltage-gated ion channels. British Journal of Pharmacology. 2015 Dec;172(24):5904-5941. https://doi.org/10.1111/bph.13349