TY - JOUR
T1 - The Concise Guide to PHARMACOLOGY 2023/24
T2 - Transporters
AU - Alexander, Stephen P H
AU - Fabbro, Doriano
AU - Kelly, Eamonn
AU - Mathie, Alistair A
AU - Peters, John A
AU - Veale, Emma L
AU - Armstrong, Jane F
AU - Faccenda, Elena
AU - Harding, Simon D
AU - Davies, Jamie A
AU - Amarosi, Laura
AU - Anderson, Catriona M H
AU - Beart, Philip M
AU - Broer, Stefan
AU - Dawson, Paul A
AU - Gyimesi, Gergely
AU - Hagenbuch, Bruno
AU - Hammond, James R
AU - Hancox, Jules C
AU - Hershfinkel, Michal
AU - Inui, Ken-Ichi
AU - Kanai, Yoshikatsu
AU - Kemp, Stephan
AU - Kunji, Edmund R S
AU - Stewart, Gavin
AU - Tavoulari, Sotiria
AU - Thwaites, David T
AU - Verri, Tiziano
N1 - © 2023 The Authors. British Journal of Pharmacology published by John Wiley & Sons Ltd on behalf of The British Pharmacological Society.
PY - 2023/12/20
Y1 - 2023/12/20
N2 - The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16182. Transporters are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
AB - The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and over 6000 interactions with about 3900 ligands. There is an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (https://www.guidetopharmacology.org/), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes almost 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.16182. Transporters are one of the six major pharmacological targets into which the Guide is divided, with the others being: G protein-coupled receptors, ion channels, nuclear hormone receptors, catalytic receptors and enzymes. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2023, and supersedes data presented in the 2021/22, 2019/20, 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the Nomenclature and Standards Committee of the International Union of Basic and Clinical Pharmacology (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.
KW - Humans
KW - Databases, Pharmaceutical
KW - Ligands
KW - Ion Channels/chemistry
KW - Receptors, G-Protein-Coupled
KW - Receptors, Cytoplasmic and Nuclear
KW - Pharmacology
U2 - 10.1111/bph.16182
DO - 10.1111/bph.16182
M3 - Article
C2 - 38123156
SN - 0007-1188
VL - 180
SP - S374-S469
JO - British Journal of Pharmacology
JF - British Journal of Pharmacology
IS - S2
ER -