The cost-effectiveness of tailored, postal feedback on general practitioners' prescribing of pharmacotherapies for alcohol dependence

TY - JOUR

T1 - The cost-effectiveness of tailored, postal feedback on general practitioners' prescribing of pharmacotherapies for alcohol dependence

AU - Navarro, Hector Jose

AU - Shakeshaft, Anthony

AU - Doran, Christopher M.

AU - Petrie, Dennis J.

N1 - Copyright 2012 Elsevier B.V., All rights reserved.

PY - 2012

Y1 - 2012

N2 - Aims: The aims of this study were to conduct a randomised controlled trial to evaluate the cost-effectiveness of tailored, postal feedback on general practitioners' (GPs) prescribing of acamprosate and naltrexone for alcohol dependence relative to current practice and its impact on alcohol dependence morbidity. Methods: Rural communities in New South Wales, Australia, were randomised into experimental (N= 10) and control (N= 10) communities. Tailored feedback on their prescribing of alcohol pharmacotherapies was mailed to GPs from the experimental communities (N= 115). Segmented regression analysis was used to examine within and between group changes in prescribing and alcohol dependence hospitalisation rates compared to the control communities. Incremental cost-effectiveness ratios (ICERs) were estimated per additional prescription of pharmacotherapies and per alcohol dependence hospitalisation(s) averted. Results: Post-intervention changes, relative to the control communities, in GPs' prescribing rate trends in the experimental communities significantly increased for acamprosate (ß= 0.24, 95% CI: 0.13-0.35, p

AB - Aims: The aims of this study were to conduct a randomised controlled trial to evaluate the cost-effectiveness of tailored, postal feedback on general practitioners' (GPs) prescribing of acamprosate and naltrexone for alcohol dependence relative to current practice and its impact on alcohol dependence morbidity. Methods: Rural communities in New South Wales, Australia, were randomised into experimental (N= 10) and control (N= 10) communities. Tailored feedback on their prescribing of alcohol pharmacotherapies was mailed to GPs from the experimental communities (N= 115). Segmented regression analysis was used to examine within and between group changes in prescribing and alcohol dependence hospitalisation rates compared to the control communities. Incremental cost-effectiveness ratios (ICERs) were estimated per additional prescription of pharmacotherapies and per alcohol dependence hospitalisation(s) averted. Results: Post-intervention changes, relative to the control communities, in GPs' prescribing rate trends in the experimental communities significantly increased for acamprosate (ß= 0.24, 95% CI: 0.13-0.35, p

UR - https://www.scopus.com/pages/publications/84864010991

U2 - 10.1016/j.drugalcdep.2012.01.007

DO - 10.1016/j.drugalcdep.2012.01.007

M3 - Article

C2 - 22361211

AN - SCOPUS:84864010991

SN - 0376-8716

VL - 124

SP - 207

EP - 215

JO - Drug and Alcohol Dependence

JF - Drug and Alcohol Dependence

IS - 3

ER -