The critical role of mode of action studies in kinetoplastid drug discovery

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• Active

  A Platform for Drug Target Deconvolution and Exploitation

  Gilbert, I. (Investigator), Horn, D. (Investigator), Pawlowic, M. C. (Investigator), Wyatt, P. (Investigator) & Wyllie, S. (Investigator)

  31/12/20 → 30/03/25

  Project: Research

  • Chagas Disease 100%
  • Visceral Leishmaniasis 72%
  • Drug Discovery 67%
  • Molecular Targets 67%
  • Mode of Action 64%

• Wellcome Centre for Anti-Infectives Research

  Cook, S. (Investigator), De Rycker, M. (Investigator), Fairlamb, A. (Investigator), Ferguson, M. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator), Pawlowic, M. C. (Investigator), Read, K. (Investigator), Wyatt, P. (Investigator) & Wyllie, S. (Investigator)

  1/04/17 → 31/03/25

  Project: Research

  • Drug Discovery 100%
  • Trypanosoma Cruzi (T. cruzi) 73%
  • Chagas Disease 66%
  • Visceral Leishmaniasis 61%
  • Trypanosoma Cruzi 61%
• Finished

  Chemical Biology: Leveraging Phenotypic Hits Against Kinetoplastids (Strategic Grant)

  Fairlamb, A. (Investigator), Field, M. (Investigator), Gilbert, I. (Investigator), Gray, D. (Investigator), Horn, D. (Investigator) & Wyatt, P. (Investigator)

  1/01/15 → 31/12/20

  Project: Research

  • Visceral Leishmaniasis 100%
  • Drug Discovery 99%
  • Leishmania Donovani 82%
  • Chagas Disease 74%
  • Drug Target 69%