The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function

J.B. Vorstius; R.P. Keatch; K. Donnelly; P.S. Maher

doi:10.1007/978-3-642-03900-3_37

The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function

J.B. Vorstius, R.P. Keatch, K. Donnelly, P.S. Maher

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Citations (Scopus)

Abstract

This paper describes the development of novel bioreactor systems for use in studying the development of tissue engineered muscle constructs. The bioreactor systems combine two environmental stimuli, mechanical loading and electrical pulses which, independently, are known to promote muscle tissue growth, into a single system to investigate whether further functional improvements can be achieved. The bioreactors are reprogrammable to enable different stimulation protocols to be assessed and allow the simultaneous stimulation of up to six tissues in a single system. This allows us to improve experimental throughput and speeds up our understanding of the physiological processes involved in skeletal muscle development.

Original language	English
Title of host publication	IFMBE Proceedings
Subtitle of host publication	World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.
Editors	Olaf Dössel, Wolfgang C. Schlegel
Place of Publication	Berlin & Heidelberg
Publisher	Springer
Pages	126-129
Number of pages	4
Volume	25
Edition	10
ISBN (Electronic)	9783642039003
ISBN (Print)	9783642038990
DOIs	https://doi.org/10.1007/978-3-642-03900-3_37
Publication status	Published - 1 Jan 2009

Access to Document

10.1007/978-3-642-03900-3_37

Cite this

Vorstius, J. B., Keatch, R. P., Donnelly, K., & Maher, P. S. (2009). The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function. In O. Dössel, & W. C. Schlegel (Eds.), IFMBE Proceedings: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany. (10 ed., Vol. 25, pp. 126-129). Springer . https://doi.org/10.1007/978-3-642-03900-3_37

Vorstius, J.B. ; Keatch, R.P. ; Donnelly, K. et al. / The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function. IFMBE Proceedings: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.. editor / Olaf Dössel ; Wolfgang C. Schlegel. Vol. 25 10. ed. Berlin & Heidelberg : Springer , 2009. pp. 126-129

@inbook{824e591f3ecc4174a470077b7760c2c0,

title = "The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function",

abstract = "This paper describes the development of novel bioreactor systems for use in studying the development of tissue engineered muscle constructs. The bioreactor systems combine two environmental stimuli, mechanical loading and electrical pulses which, independently, are known to promote muscle tissue growth, into a single system to investigate whether further functional improvements can be achieved. The bioreactors are reprogrammable to enable different stimulation protocols to be assessed and allow the simultaneous stimulation of up to six tissues in a single system. This allows us to improve experimental throughput and speeds up our understanding of the physiological processes involved in skeletal muscle development.",

author = "J.B. Vorstius and R.P. Keatch and K. Donnelly and P.S. Maher",

year = "2009",

month = jan,

day = "1",

doi = "10.1007/978-3-642-03900-3_37",

language = "English",

isbn = "9783642038990",

volume = "25",

pages = "126--129",

editor = "Olaf D{\"o}ssel and Schlegel, {Wolfgang C.}",

booktitle = "IFMBE Proceedings",

publisher = "Springer ",

edition = "10",

}

Vorstius, JB , Keatch, RP, Donnelly, K & Maher, PS 2009, The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function. in O Dössel & WC Schlegel (eds), IFMBE Proceedings: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.. 10 edn, vol. 25, Springer , Berlin & Heidelberg, pp. 126-129. https://doi.org/10.1007/978-3-642-03900-3_37

The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function. / Vorstius, J.B.; Keatch, R.P.; Donnelly, K. et al.
IFMBE Proceedings: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.. ed. / Olaf Dössel; Wolfgang C. Schlegel. Vol. 25 10. ed. Berlin & Heidelberg: Springer , 2009. p. 126-129.

Research output: Chapter in Book/Report/Conference proceeding › Chapter

TY - CHAP

T1 - The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function

AU - Vorstius, J.B.

AU - Keatch, R.P.

AU - Donnelly, K.

AU - Maher, P.S.

PY - 2009/1/1

Y1 - 2009/1/1

N2 - This paper describes the development of novel bioreactor systems for use in studying the development of tissue engineered muscle constructs. The bioreactor systems combine two environmental stimuli, mechanical loading and electrical pulses which, independently, are known to promote muscle tissue growth, into a single system to investigate whether further functional improvements can be achieved. The bioreactors are reprogrammable to enable different stimulation protocols to be assessed and allow the simultaneous stimulation of up to six tissues in a single system. This allows us to improve experimental throughput and speeds up our understanding of the physiological processes involved in skeletal muscle development.

AB - This paper describes the development of novel bioreactor systems for use in studying the development of tissue engineered muscle constructs. The bioreactor systems combine two environmental stimuli, mechanical loading and electrical pulses which, independently, are known to promote muscle tissue growth, into a single system to investigate whether further functional improvements can be achieved. The bioreactors are reprogrammable to enable different stimulation protocols to be assessed and allow the simultaneous stimulation of up to six tissues in a single system. This allows us to improve experimental throughput and speeds up our understanding of the physiological processes involved in skeletal muscle development.

UR - http://www.scopus.com/inward/record.url?scp=77950133971&partnerID=8YFLogxK

U2 - 10.1007/978-3-642-03900-3_37

DO - 10.1007/978-3-642-03900-3_37

M3 - Chapter

AN - SCOPUS:77950133971

SN - 9783642038990

VL - 25

SP - 126

EP - 129

BT - IFMBE Proceedings

A2 - Dössel, Olaf

A2 - Schlegel, Wolfgang C.

PB - Springer

CY - Berlin & Heidelberg

ER -

Vorstius JB , Keatch RP, Donnelly K, Maher PS. The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function. In Dössel O, Schlegel WC, editors, IFMBE Proceedings: World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany.. 10 ed. Vol. 25. Berlin & Heidelberg: Springer . 2009. p. 126-129 doi: 10.1007/978-3-642-03900-3_37

The development of a combined electrical & mechanical stimulation bioreactor to improve tissue engineered muscle function

Abstract

Access to Document

Other files and links

Fingerprint

Cite this