The devil’s in the detail: cell-specific role of PPARγ in ILC2 activation by IL-33

Henry J. McSorley (Lead / Corresponding author), J. Simon C. Arthur

Research output: Contribution to journalComment/debatepeer-review

Abstract

PPARγ is a critical transcriptional regulator of adipogenesis and type 2 immune responses, however until recently its role in type 2 innate lymphoid cells had not been characterised. In two papers in this issue of Mucosal Immunology, PPARγ is shown to have a dominant role in ILC2 responses, mediating IL-33-responsiveness and activation.
Original languageEnglish
Pages (from-to)544-546
Number of pages3
JournalMucosal Immunology
Volume14
Early online date16 Dec 2020
DOIs
Publication statusPublished - May 2021

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