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PPARγ is a critical transcriptional regulator of adipogenesis and type 2 immune responses, however until recently its role in type 2 innate lymphoid cells had not been characterised. In two papers in this issue of Mucosal Immunology, PPARγ is shown to have a dominant role in ILC2 responses, mediating IL-33-responsiveness and activation.
FingerprintDive into the research topics of 'The devil’s in the detail: cell-specific role of PPARγ in ILC2 activation by IL-33'. Together they form a unique fingerprint.
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1/02/20 → 31/01/22