The diverse structures and functions of surfactant proteins

Marieke Schor, Jack L. Reid , Cait E. MacPhee (Lead / Corresponding author), Nicola Stanley-Wall (Lead / Corresponding author)

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)
209 Downloads (Pure)


Surface tension at liquid-air interfaces is a major barrier that needs to be surmounted by a wide range of organisms; surfactant and interfacially-active proteins have evolved for this purpose. Although these proteins are essential for a variety of biological processes, our understanding of how they elicit their function has been limited. However, with the recent determination of high resolution 3D structures of several examples, we have gained insight into the distinct shapes and mechanisms that have evolved to confer interfacial activity. It is now a matter of harnessing this information, and these systems, for biotechnological purposes.
Original languageEnglish
Pages (from-to)610-620
Number of pages11
JournalTrends in Biochemical Sciences
Issue number7
Early online date27 May 2016
Publication statusPublished - Jul 2016


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