The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer

John D. Hayes, Michael McMahon

    Research output: Contribution to journalArticlepeer-review

    91 Citations (Scopus)

    Abstract

    Low levels of Nrf2 activity predispose cells to chemical carcinogenesis. Surprisingly, Padmanabhan et al. (2006) provide evidence in a recent issue of Molecular Cell to support the notion that elevated Nrf2 activity may also play a role in the evolution of cancer.
    Original languageEnglish
    Pages (from-to)732-4
    Number of pages3
    JournalMolecular Cell
    Volume21
    Issue number6
    DOIs
    Publication statusPublished - 2006

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