The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer

John D. Hayes; Michael McMahon

doi:10.1016/j.molcel.2006.03.004

The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer

John D. Hayes, Michael McMahon

Research output: Contribution to journal › Article › peer-review

120 Citations (Scopus)

Abstract

Low levels of Nrf2 activity predispose cells to chemical carcinogenesis. Surprisingly, Padmanabhan et al. (2006) provide evidence in a recent issue of Molecular Cell to support the notion that elevated Nrf2 activity may also play a role in the evolution of cancer.

Original language	English
Pages (from-to)	732-4
Number of pages	3
Journal	Molecular Cell
Volume	21
Issue number	6
DOIs	https://doi.org/10.1016/j.molcel.2006.03.004
Publication status	Published - 2006

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10.1016/j.molcel.2006.03.004

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title = "The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer",

abstract = "Low levels of Nrf2 activity predispose cells to chemical carcinogenesis. Surprisingly, Padmanabhan et al. (2006) provide evidence in a recent issue of Molecular Cell to support the notion that elevated Nrf2 activity may also play a role in the evolution of cancer.",

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AU - McMahon, Michael

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AB - Low levels of Nrf2 activity predispose cells to chemical carcinogenesis. Surprisingly, Padmanabhan et al. (2006) provide evidence in a recent issue of Molecular Cell to support the notion that elevated Nrf2 activity may also play a role in the evolution of cancer.

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DO - 10.1016/j.molcel.2006.03.004

M3 - Article

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SN - 1097-2765

VL - 21

SP - 732

EP - 734

JO - Molecular Cell

JF - Molecular Cell

IS - 6

ER -

The double-edged sword of Nrf2: subversion of redox homeostasis during the evolution of cancer

Abstract

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