The Dundee Resource for Sequence Analysis and Structure Prediction

Stuart MacGowan, Fabio Madeira, Thiago Britto-Borges, Mateusz Warowny, Alexey Drozdetskiy, James Procter, Geoffrey Barton (Lead / Corresponding author)

Research output: Contribution to journalArticle

10 Downloads (Pure)

Abstract

The Dundee Resource for Sequence Analysis and Structure Prediction (DRSASP; http://www.compbio.dundee.ac.uk/drsasp.html) is a collection of web services provided by the Barton Group at the University of Dundee. DRSASP's flagship services are the JPred4 webserver for secondary structure and solvent accessibility prediction and the JABAWS 2.2 webserver for multiple sequence alignment, disorder prediction, amino acid conservation calculations and specificity determining site prediction. DRSASP resources are available through conventional web interfaces and APIs but are also integrated into the Jalview sequence analysis workbench which enables the composition of multitool interactive workflows. Other existing Barton Group tools are being brought under the banner of DRSASP, including NoD (Nucleolar localisation sequence detector) and 14‐3‐3‐Pred. New resources are being developed that enable the analysis of population genetic data in evolutionary and 3D structural contexts. Existing resources are actively developed to exploit new technologies and maintain parity with evolving web standards. DRSASP provides substantial computational resources for public use and since 2016 DRSASP services have completed over 1.5 million jobs.
Original languageEnglish
JournalProtein Science
Early online date11 Nov 2019
DOIs
Publication statusE-pub ahead of print - 11 Nov 2019

Fingerprint

Sequence Analysis
Workflow
Sequence Alignment
Population Genetics
Parity
Technology
Amino Acids
Application programming interfaces (API)
Web services
Interfaces (computer)
Conservation
Detectors
Chemical analysis

Cite this

@article{a2509045050a4d4080827573dbe42c1d,
title = "The Dundee Resource for Sequence Analysis and Structure Prediction",
abstract = "The Dundee Resource for Sequence Analysis and Structure Prediction (DRSASP; http://www.compbio.dundee.ac.uk/drsasp.html) is a collection of web services provided by the Barton Group at the University of Dundee. DRSASP's flagship services are the JPred4 webserver for secondary structure and solvent accessibility prediction and the JABAWS 2.2 webserver for multiple sequence alignment, disorder prediction, amino acid conservation calculations and specificity determining site prediction. DRSASP resources are available through conventional web interfaces and APIs but are also integrated into the Jalview sequence analysis workbench which enables the composition of multitool interactive workflows. Other existing Barton Group tools are being brought under the banner of DRSASP, including NoD (Nucleolar localisation sequence detector) and 14‐3‐3‐Pred. New resources are being developed that enable the analysis of population genetic data in evolutionary and 3D structural contexts. Existing resources are actively developed to exploit new technologies and maintain parity with evolving web standards. DRSASP provides substantial computational resources for public use and since 2016 DRSASP services have completed over 1.5 million jobs.",
author = "Stuart MacGowan and Fabio Madeira and Thiago Britto-Borges and Mateusz Warowny and Alexey Drozdetskiy and James Procter and Geoffrey Barton",
note = "We are grateful to all authors of methods that have been included in DRSASP. We thank Tom Walsh and the Dundee Research Computing team for supporting our IT infrastructure and James Abbott for his expert sysadmin advice. This work was supported by Biotechnology and Biological Sciences Research Council Grants [BB/J019364/1 and BB/R014752/1] and Wellcome Trust Biomedical Resources Grant [101651/Z/13/Z].",
year = "2019",
month = "11",
day = "11",
doi = "10.1002/pro.3783",
language = "English",
journal = "Protein Science",
issn = "0961-8368",
publisher = "Wiley",

}

The Dundee Resource for Sequence Analysis and Structure Prediction. / MacGowan, Stuart; Madeira, Fabio; Britto-Borges, Thiago ; Warowny, Mateusz ; Drozdetskiy, Alexey; Procter, James; Barton, Geoffrey (Lead / Corresponding author).

In: Protein Science, 11.11.2019.

Research output: Contribution to journalArticle

TY - JOUR

T1 - The Dundee Resource for Sequence Analysis and Structure Prediction

AU - MacGowan, Stuart

AU - Madeira, Fabio

AU - Britto-Borges, Thiago

AU - Warowny, Mateusz

AU - Drozdetskiy, Alexey

AU - Procter, James

AU - Barton, Geoffrey

N1 - We are grateful to all authors of methods that have been included in DRSASP. We thank Tom Walsh and the Dundee Research Computing team for supporting our IT infrastructure and James Abbott for his expert sysadmin advice. This work was supported by Biotechnology and Biological Sciences Research Council Grants [BB/J019364/1 and BB/R014752/1] and Wellcome Trust Biomedical Resources Grant [101651/Z/13/Z].

PY - 2019/11/11

Y1 - 2019/11/11

N2 - The Dundee Resource for Sequence Analysis and Structure Prediction (DRSASP; http://www.compbio.dundee.ac.uk/drsasp.html) is a collection of web services provided by the Barton Group at the University of Dundee. DRSASP's flagship services are the JPred4 webserver for secondary structure and solvent accessibility prediction and the JABAWS 2.2 webserver for multiple sequence alignment, disorder prediction, amino acid conservation calculations and specificity determining site prediction. DRSASP resources are available through conventional web interfaces and APIs but are also integrated into the Jalview sequence analysis workbench which enables the composition of multitool interactive workflows. Other existing Barton Group tools are being brought under the banner of DRSASP, including NoD (Nucleolar localisation sequence detector) and 14‐3‐3‐Pred. New resources are being developed that enable the analysis of population genetic data in evolutionary and 3D structural contexts. Existing resources are actively developed to exploit new technologies and maintain parity with evolving web standards. DRSASP provides substantial computational resources for public use and since 2016 DRSASP services have completed over 1.5 million jobs.

AB - The Dundee Resource for Sequence Analysis and Structure Prediction (DRSASP; http://www.compbio.dundee.ac.uk/drsasp.html) is a collection of web services provided by the Barton Group at the University of Dundee. DRSASP's flagship services are the JPred4 webserver for secondary structure and solvent accessibility prediction and the JABAWS 2.2 webserver for multiple sequence alignment, disorder prediction, amino acid conservation calculations and specificity determining site prediction. DRSASP resources are available through conventional web interfaces and APIs but are also integrated into the Jalview sequence analysis workbench which enables the composition of multitool interactive workflows. Other existing Barton Group tools are being brought under the banner of DRSASP, including NoD (Nucleolar localisation sequence detector) and 14‐3‐3‐Pred. New resources are being developed that enable the analysis of population genetic data in evolutionary and 3D structural contexts. Existing resources are actively developed to exploit new technologies and maintain parity with evolving web standards. DRSASP provides substantial computational resources for public use and since 2016 DRSASP services have completed over 1.5 million jobs.

U2 - 10.1002/pro.3783

DO - 10.1002/pro.3783

M3 - Article

C2 - 31710725

JO - Protein Science

JF - Protein Science

SN - 0961-8368

ER -