The Dundee University Scottish Keratoconus Study II

a prospective study of optical and surgical correction

K. H. Weed, C. J. MacEwen, C. N. J. McGhee

    Research output: Contribution to journalArticle

    28 Citations (Scopus)

    Abstract

    Aim: To investigate and correlate optical correction, and progression to penetrating keratoplasty (PKP), with the corneal, refractive, topographic and familial characteristics of subjects with keratoconus, within the Tayside region of Scotland. Method: Prospective, observational, longitudinal study design. Two hundred subjects with keratoconus were enrolled into the Dundee University Scottish Keratoconus Study (DUSKS) and were assessed during a 4-year period using standardised clinical assessment, computerised corneal topography and questionnaires. Results: Keratoconic subjects in this study wore rigid contact lenses (90.6%) for longer than 12 hours per day (81%), 7 days a week (91%) and achieved a very good level of Snellen visual acuity (97%, =6/9). Corneal staining was observed in the majority of corneas (71%), although only a small percentage of subjects reported major problems of: discomfort (18%), hyperaemia (16%), or the lens falling out (4%). Poor visual acuity was the main reason (79%) for undergoing PKP usually in the latter part of the third decade of life, approximately a decade after diagnosis. During the study period 4% of eyes progressed to PKP. Only a small percentage of eyes (9.5%) required no visual correction postoperatively. Conclusion: The main mode of visual rehabilitation for keratoconus was rigid contact lenses, which were mostly worn successfully with good visual acuity. During the study period a small minority of keratoconics progressed to corneal graft surgery. It is advisable to emphasise that postoperatively refractive correction will be required in the majority of these cases. © 2007 The Authors.
    Original languageEnglish
    Pages (from-to)561-567
    Number of pages7
    JournalOphthalmic and Physiological Optics
    Volume27
    Issue number6
    DOIs
    Publication statusPublished - Nov 2007

    Fingerprint

    Keratoconus
    Penetrating Keratoplasty
    Prospective Studies
    Visual Acuity
    Contact Lenses
    Corneal Topography
    Hyperemia
    Scotland
    Cornea
    Lenses
    Observational Studies
    Longitudinal Studies
    Rehabilitation
    Staining and Labeling
    Transplants

    Keywords

    • Adolescent
    • Adult
    • Contact Lenses
    • Female
    • Humans
    • Keratoconus
    • Keratoplasty, Penetrating
    • Longitudinal Studies
    • Male
    • Prospective Studies
    • Scotland
    • Vision Disorders
    • Visual Acuity

    Cite this

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    title = "The Dundee University Scottish Keratoconus Study II: a prospective study of optical and surgical correction",
    abstract = "Aim: To investigate and correlate optical correction, and progression to penetrating keratoplasty (PKP), with the corneal, refractive, topographic and familial characteristics of subjects with keratoconus, within the Tayside region of Scotland. Method: Prospective, observational, longitudinal study design. Two hundred subjects with keratoconus were enrolled into the Dundee University Scottish Keratoconus Study (DUSKS) and were assessed during a 4-year period using standardised clinical assessment, computerised corneal topography and questionnaires. Results: Keratoconic subjects in this study wore rigid contact lenses (90.6{\%}) for longer than 12 hours per day (81{\%}), 7 days a week (91{\%}) and achieved a very good level of Snellen visual acuity (97{\%}, =6/9). Corneal staining was observed in the majority of corneas (71{\%}), although only a small percentage of subjects reported major problems of: discomfort (18{\%}), hyperaemia (16{\%}), or the lens falling out (4{\%}). Poor visual acuity was the main reason (79{\%}) for undergoing PKP usually in the latter part of the third decade of life, approximately a decade after diagnosis. During the study period 4{\%} of eyes progressed to PKP. Only a small percentage of eyes (9.5{\%}) required no visual correction postoperatively. Conclusion: The main mode of visual rehabilitation for keratoconus was rigid contact lenses, which were mostly worn successfully with good visual acuity. During the study period a small minority of keratoconics progressed to corneal graft surgery. It is advisable to emphasise that postoperatively refractive correction will be required in the majority of these cases. {\circledC} 2007 The Authors.",
    keywords = "Adolescent, Adult, Contact Lenses, Female, Humans, Keratoconus, Keratoplasty, Penetrating, Longitudinal Studies, Male, Prospective Studies, Scotland, Vision Disorders, Visual Acuity",
    author = "Weed, {K. H.} and MacEwen, {C. J.} and McGhee, {C. N. J.}",
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    The Dundee University Scottish Keratoconus Study II : a prospective study of optical and surgical correction. / Weed, K. H.; MacEwen, C. J.; McGhee, C. N. J.

    In: Ophthalmic and Physiological Optics, Vol. 27, No. 6, 11.2007, p. 561-567.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - The Dundee University Scottish Keratoconus Study II

    T2 - a prospective study of optical and surgical correction

    AU - Weed, K. H.

    AU - MacEwen, C. J.

    AU - McGhee, C. N. J.

    PY - 2007/11

    Y1 - 2007/11

    N2 - Aim: To investigate and correlate optical correction, and progression to penetrating keratoplasty (PKP), with the corneal, refractive, topographic and familial characteristics of subjects with keratoconus, within the Tayside region of Scotland. Method: Prospective, observational, longitudinal study design. Two hundred subjects with keratoconus were enrolled into the Dundee University Scottish Keratoconus Study (DUSKS) and were assessed during a 4-year period using standardised clinical assessment, computerised corneal topography and questionnaires. Results: Keratoconic subjects in this study wore rigid contact lenses (90.6%) for longer than 12 hours per day (81%), 7 days a week (91%) and achieved a very good level of Snellen visual acuity (97%, =6/9). Corneal staining was observed in the majority of corneas (71%), although only a small percentage of subjects reported major problems of: discomfort (18%), hyperaemia (16%), or the lens falling out (4%). Poor visual acuity was the main reason (79%) for undergoing PKP usually in the latter part of the third decade of life, approximately a decade after diagnosis. During the study period 4% of eyes progressed to PKP. Only a small percentage of eyes (9.5%) required no visual correction postoperatively. Conclusion: The main mode of visual rehabilitation for keratoconus was rigid contact lenses, which were mostly worn successfully with good visual acuity. During the study period a small minority of keratoconics progressed to corneal graft surgery. It is advisable to emphasise that postoperatively refractive correction will be required in the majority of these cases. © 2007 The Authors.

    AB - Aim: To investigate and correlate optical correction, and progression to penetrating keratoplasty (PKP), with the corneal, refractive, topographic and familial characteristics of subjects with keratoconus, within the Tayside region of Scotland. Method: Prospective, observational, longitudinal study design. Two hundred subjects with keratoconus were enrolled into the Dundee University Scottish Keratoconus Study (DUSKS) and were assessed during a 4-year period using standardised clinical assessment, computerised corneal topography and questionnaires. Results: Keratoconic subjects in this study wore rigid contact lenses (90.6%) for longer than 12 hours per day (81%), 7 days a week (91%) and achieved a very good level of Snellen visual acuity (97%, =6/9). Corneal staining was observed in the majority of corneas (71%), although only a small percentage of subjects reported major problems of: discomfort (18%), hyperaemia (16%), or the lens falling out (4%). Poor visual acuity was the main reason (79%) for undergoing PKP usually in the latter part of the third decade of life, approximately a decade after diagnosis. During the study period 4% of eyes progressed to PKP. Only a small percentage of eyes (9.5%) required no visual correction postoperatively. Conclusion: The main mode of visual rehabilitation for keratoconus was rigid contact lenses, which were mostly worn successfully with good visual acuity. During the study period a small minority of keratoconics progressed to corneal graft surgery. It is advisable to emphasise that postoperatively refractive correction will be required in the majority of these cases. © 2007 The Authors.

    KW - Adolescent

    KW - Adult

    KW - Contact Lenses

    KW - Female

    KW - Humans

    KW - Keratoconus

    KW - Keratoplasty, Penetrating

    KW - Longitudinal Studies

    KW - Male

    KW - Prospective Studies

    KW - Scotland

    KW - Vision Disorders

    KW - Visual Acuity

    U2 - 10.1111/j.1475-1313.2007.00524.x

    DO - 10.1111/j.1475-1313.2007.00524.x

    M3 - Article

    VL - 27

    SP - 561

    EP - 567

    JO - Ophthalmic and Physiological Optics

    JF - Ophthalmic and Physiological Optics

    SN - 0275-5408

    IS - 6

    ER -