The early diagnosis of oesophageal adenocarcinoma by endoscopic screening

M. Atkinson, S. Y. Iftikhar, P. D. James, Catherine Robertson, R. J. C. Steele

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    17 Citations (Scopus)


    Oesophageal carcinoma has a very poor prognosis unless detected at a pre-symptomatic stage. This can only be done by screening and patients with Barrett's columnar lined epithelium of the oesophagus (CLO) are high risk candidates for an endoscopic screening programme. Surveillance studies in CLO patients, when reviewed, showed that the incidence of adenocarcinoma was between 1 in 52 and 1 in 81 patient years, with a mean of 1 in 76. This paper describes the Nottingham experience with an endoscopic screening programme that was established in 1976. To date it has detected four adenocarcinomas at a mean cost similar to that of detecting breast cancer by screening.
    Original languageEnglish
    Pages (from-to)327-330
    Number of pages4
    JournalEuropean Journal of Cancer Prevention
    Issue number4
    Publication statusPublished - 1992


    • Adenocarcinoma
    • Barrett Esophagus
    • Biological Markers
    • England
    • Esophageal Neoplasms
    • Esophagoscopy
    • Follow-Up Studies
    • Hospitals, University
    • Humans
    • Incidence
    • Mass Screening
    • Outcome Assessment (Health Care)
    • Population Surveillance
    • Questionnaires


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