The effect of atrial natriuretic factor on urinary albumin and β2-microglobulin excretion in man

John McMurray; Peter H. Seidelin; Jacqui E. A. Howey; David J. Balfour; Allan D. Struthers

The effect of atrial natriuretic factor on urinary albumin and β2-microglobulin excretion in man

John McMurray, Peter H. Seidelin, Jacqui E. A. Howey, David J. Balfour, Allan D. Struthers

Research output: Contribution to journal › Article › peer-review

Abstract

TThe effect of a 20-min infusion of atrial natriuretic factor (ANF) 99-126, 0.4 µg/kg per min, on both urinary albumin and ß2-microglobulin was examined in nine normal male subjects during stable water diuresis. ANF caused a rise in urinary albumin in excretion (from 4.19 ± 0.66 to 13.49 ± 3.07 ng/min, P < 0.01) without any significant change in either creatinine clearance of ß2-microglobulin excretion. These findings suggest that ANF may enhance glomerular permeability to albumin in man.

Original language	English
Pages (from-to)	783-786
Number of pages	4
Journal	Journal of Hypertension
Volume	6
Issue number	10
Publication status	Published - 1988

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title = "The effect of atrial natriuretic factor on urinary albumin and β2-microglobulin excretion in man",

abstract = "TThe effect of a 20-min infusion of atrial natriuretic factor (ANF) 99-126, 0.4 µg/kg per min, on both urinary albumin and {\ss}2-microglobulin was examined in nine normal male subjects during stable water diuresis. ANF caused a rise in urinary albumin in excretion (from 4.19 ± 0.66 to 13.49 ± 3.07 ng/min, P < 0.01) without any significant change in either creatinine clearance of {\ss}2-microglobulin excretion. These findings suggest that ANF may enhance glomerular permeability to albumin in man.",

author = "John McMurray and Seidelin, {Peter H.} and Howey, {Jacqui E. A.} and Balfour, {David J.} and Struthers, {Allan D.}",

year = "1988",

language = "English",

volume = "6",

pages = "783--786",

journal = "Journal of Hypertension",

issn = "0263-6352",

publisher = "Lippincott Williams and Wilkins",

number = "10",

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TY - JOUR

T1 - The effect of atrial natriuretic factor on urinary albumin and β2-microglobulin excretion in man

AU - McMurray, John

AU - Seidelin, Peter H.

AU - Howey, Jacqui E. A.

AU - Balfour, David J.

AU - Struthers, Allan D.

PY - 1988

Y1 - 1988

N2 - TThe effect of a 20-min infusion of atrial natriuretic factor (ANF) 99-126, 0.4 µg/kg per min, on both urinary albumin and ß2-microglobulin was examined in nine normal male subjects during stable water diuresis. ANF caused a rise in urinary albumin in excretion (from 4.19 ± 0.66 to 13.49 ± 3.07 ng/min, P < 0.01) without any significant change in either creatinine clearance of ß2-microglobulin excretion. These findings suggest that ANF may enhance glomerular permeability to albumin in man.

AB - TThe effect of a 20-min infusion of atrial natriuretic factor (ANF) 99-126, 0.4 µg/kg per min, on both urinary albumin and ß2-microglobulin was examined in nine normal male subjects during stable water diuresis. ANF caused a rise in urinary albumin in excretion (from 4.19 ± 0.66 to 13.49 ± 3.07 ng/min, P < 0.01) without any significant change in either creatinine clearance of ß2-microglobulin excretion. These findings suggest that ANF may enhance glomerular permeability to albumin in man.

M3 - Article

C2 - 2974052

VL - 6

SP - 783

EP - 786

JO - Journal of Hypertension

JF - Journal of Hypertension

SN - 0263-6352

IS - 10

ER -