The effect of atrial natriuretic factor on urinary albumin and β2-microglobulin excretion in man

John McMurray, Peter H. Seidelin, Jacqui E. A. Howey, David J. Balfour, Allan D. Struthers

    Research output: Contribution to journalArticle

    26 Citations (Scopus)

    Abstract

    TThe effect of a 20-min infusion of atrial natriuretic factor (ANF) 99-126, 0.4 µg/kg per min, on both urinary albumin and ß2-microglobulin was examined in nine normal male subjects during stable water diuresis. ANF caused a rise in urinary albumin in excretion (from 4.19 ± 0.66 to 13.49 ± 3.07 ng/min, P < 0.01) without any significant change in either creatinine clearance of ß2-microglobulin excretion. These findings suggest that ANF may enhance glomerular permeability to albumin in man.
    Original languageEnglish
    Pages (from-to)783-786
    Number of pages4
    JournalJournal of Hypertension
    Volume6
    Issue number10
    Publication statusPublished - 1988

    Fingerprint Dive into the research topics of 'The effect of atrial natriuretic factor on urinary albumin and β2-microglobulin excretion in man'. Together they form a unique fingerprint.

  • Cite this