The effect of radiological contrast media on renal function and inflammatory markers in people with diabetes - A clinical study and review

Mark Baxter, Catherine Gooday, Ketan Dhatariya (Lead / Corresponding author)

Research output: Contribution to journalArticle

Abstract

Aim: To assess the association of inflammatory markers and the risk of developing contrast-induced nephropathy (CIN) in patients with diabetes undergoing lower limb angiography.
Methods: This was a retrospective study of 77 patients undergoing lower limb angiography. We measured renal function and markers of inflammation, in particular neutrophil and lymphocyte count and C-reactive protein (CRP) levels, before and at 24, 48 and 72 hours after administration of contrast medium.
Results: Those with pre-existing renal disease were at increased risk of CIN. We found no relationship between baseline renal function and CRP. There was a reduction in haemoglobin and lymphocyte count that is currently unexplained.
Conclusions: While several traditional risk factors for CIN have been identified, further work is needed to determine the significance of changes in other haematological parameters.
Original languageEnglish
Pages (from-to)187-191
Number of pages5
JournalThe British Journal of Diabetes & Vascular Disease
Volume15
Issue number4
DOIs
Publication statusPublished - 2015

Keywords

  • diabetes
  • angiography
  • contrast
  • contrast-induced nephropathy
  • inflammatory markers

Fingerprint Dive into the research topics of 'The effect of radiological contrast media on renal function and inflammatory markers in people with diabetes - A clinical study and review'. Together they form a unique fingerprint.

Cite this