The effect of the neutral endopeptidase inhibitor drug, candoxatril, on circulating levels of two of the most potent vasoactive peptides

G McDowell, W Coutie, C Shaw, K. D. Buchanan, A D Struthers, D P Nicholls

    Research output: Contribution to journalArticle

    83 Citations (Scopus)

    Abstract

    Candoxatril is a specific neutral endopeptidase (NEP) 24.11 inhibitor, and previous work has documented the effect of NEP inhibition on atrial and brain natriuretic peptides (ANP, BNP). The aim of the present study was to ascertain the effect of NEP inhibition on circulating levels of vasoactive peptides.
    Original languageEnglish
    Pages (from-to)329-332
    Number of pages4
    JournalBritish Journal of Clinical Pharmacology
    Volume43
    Issue number3
    DOIs
    Publication statusPublished - 1997

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