The effectiveness of silver diamine fluoride in arresting caries

Derek Richards

Research output: Contribution to journalComment/debate

1 Citation (Scopus)

Abstract

Data sourcesPubMed, Embase, Scopus, China National Knowledge Infrastructure (CNKI), Ichushi-web, Biblioteca Virtual en Salud Espana (BVSE) and Biblioteca Virtual em Saude (BVS) databases. There were no limits on language or publication dates.Study selectionTwo reviewers selected prospective clinical studies investigating SDF treatment for caries prevention in children.Data extraction and synthesisData was abstracted independently by two reviewers and risk of bias assessed. Meta-analysis was performed on studies in which the caries-arresting rate using 38% SDF solution on primary teeth could be obtained or calculated.ResultsNineteen studies were included; 16 were conducted in the primary dentition and three in permanent dentition. Fourteen studies used 38% SDF, three 30% SDF, and two 10% SDF. Eight studies using 38% SDF contributed to a meta-analysis and the overall proportion of arrested caries was 81% (95% CI; 68-89%). Percentage reductions were also calculated for 6,12,18,24 and >30 months. Arrested carious lesions stained black but no other adverse effects were reported.ConclusionsSDF commonly used at a high concentration (38%, 44,800ppm fluoride) is effective in arresting caries among children. There is no consensus on its number and frequency of application to arrest caries. Further studies are necessary to develop evidence-based guidelines on its use in children.

Original languageEnglish
Pages (from-to)70
Number of pages1
JournalEvidence-Based Dentistry
Volume18
Issue number3
DOIs
Publication statusPublished - 27 Oct 2017

Fingerprint

Deciduous Tooth
Meta-Analysis
Permanent Dentition
Fluorides
Publications
China
Consensus
Language
Databases
Prospective Studies
Guidelines
silver diamine fluoride
Therapeutics
Clinical Studies

Cite this

@article{5c317e477e8745f29b201dd552bfa161,
title = "The effectiveness of silver diamine fluoride in arresting caries",
abstract = "Data sourcesPubMed, Embase, Scopus, China National Knowledge Infrastructure (CNKI), Ichushi-web, Biblioteca Virtual en Salud Espana (BVSE) and Biblioteca Virtual em Saude (BVS) databases. There were no limits on language or publication dates.Study selectionTwo reviewers selected prospective clinical studies investigating SDF treatment for caries prevention in children.Data extraction and synthesisData was abstracted independently by two reviewers and risk of bias assessed. Meta-analysis was performed on studies in which the caries-arresting rate using 38{\%} SDF solution on primary teeth could be obtained or calculated.ResultsNineteen studies were included; 16 were conducted in the primary dentition and three in permanent dentition. Fourteen studies used 38{\%} SDF, three 30{\%} SDF, and two 10{\%} SDF. Eight studies using 38{\%} SDF contributed to a meta-analysis and the overall proportion of arrested caries was 81{\%} (95{\%} CI; 68-89{\%}). Percentage reductions were also calculated for 6,12,18,24 and >30 months. Arrested carious lesions stained black but no other adverse effects were reported.ConclusionsSDF commonly used at a high concentration (38{\%}, 44,800ppm fluoride) is effective in arresting caries among children. There is no consensus on its number and frequency of application to arrest caries. Further studies are necessary to develop evidence-based guidelines on its use in children.",
author = "Derek Richards",
note = "Commentary on {"}Gao SS, Zhao IS, Hiraishi N, Duangthip D, Mei ML, Lo ECM, Chu CH. Clinical trials of silver diamine fluoride in arresting caries among children. A systematic review. JDR Clin Trans Res 2016; 1: 201–210{"}",
year = "2017",
month = "10",
day = "27",
doi = "10.1038/sj.ebd.6401250",
language = "English",
volume = "18",
pages = "70",
journal = "Evidence-Based Dentistry",
issn = "1462-0049",
publisher = "Nature Publishing Group",
number = "3",

}

The effectiveness of silver diamine fluoride in arresting caries. / Richards, Derek.

In: Evidence-Based Dentistry, Vol. 18, No. 3, 27.10.2017, p. 70.

Research output: Contribution to journalComment/debate

TY - JOUR

T1 - The effectiveness of silver diamine fluoride in arresting caries

AU - Richards, Derek

N1 - Commentary on "Gao SS, Zhao IS, Hiraishi N, Duangthip D, Mei ML, Lo ECM, Chu CH. Clinical trials of silver diamine fluoride in arresting caries among children. A systematic review. JDR Clin Trans Res 2016; 1: 201–210"

PY - 2017/10/27

Y1 - 2017/10/27

N2 - Data sourcesPubMed, Embase, Scopus, China National Knowledge Infrastructure (CNKI), Ichushi-web, Biblioteca Virtual en Salud Espana (BVSE) and Biblioteca Virtual em Saude (BVS) databases. There were no limits on language or publication dates.Study selectionTwo reviewers selected prospective clinical studies investigating SDF treatment for caries prevention in children.Data extraction and synthesisData was abstracted independently by two reviewers and risk of bias assessed. Meta-analysis was performed on studies in which the caries-arresting rate using 38% SDF solution on primary teeth could be obtained or calculated.ResultsNineteen studies were included; 16 were conducted in the primary dentition and three in permanent dentition. Fourteen studies used 38% SDF, three 30% SDF, and two 10% SDF. Eight studies using 38% SDF contributed to a meta-analysis and the overall proportion of arrested caries was 81% (95% CI; 68-89%). Percentage reductions were also calculated for 6,12,18,24 and >30 months. Arrested carious lesions stained black but no other adverse effects were reported.ConclusionsSDF commonly used at a high concentration (38%, 44,800ppm fluoride) is effective in arresting caries among children. There is no consensus on its number and frequency of application to arrest caries. Further studies are necessary to develop evidence-based guidelines on its use in children.

AB - Data sourcesPubMed, Embase, Scopus, China National Knowledge Infrastructure (CNKI), Ichushi-web, Biblioteca Virtual en Salud Espana (BVSE) and Biblioteca Virtual em Saude (BVS) databases. There were no limits on language or publication dates.Study selectionTwo reviewers selected prospective clinical studies investigating SDF treatment for caries prevention in children.Data extraction and synthesisData was abstracted independently by two reviewers and risk of bias assessed. Meta-analysis was performed on studies in which the caries-arresting rate using 38% SDF solution on primary teeth could be obtained or calculated.ResultsNineteen studies were included; 16 were conducted in the primary dentition and three in permanent dentition. Fourteen studies used 38% SDF, three 30% SDF, and two 10% SDF. Eight studies using 38% SDF contributed to a meta-analysis and the overall proportion of arrested caries was 81% (95% CI; 68-89%). Percentage reductions were also calculated for 6,12,18,24 and >30 months. Arrested carious lesions stained black but no other adverse effects were reported.ConclusionsSDF commonly used at a high concentration (38%, 44,800ppm fluoride) is effective in arresting caries among children. There is no consensus on its number and frequency of application to arrest caries. Further studies are necessary to develop evidence-based guidelines on its use in children.

U2 - 10.1038/sj.ebd.6401250

DO - 10.1038/sj.ebd.6401250

M3 - Comment/debate

C2 - 29075024

VL - 18

SP - 70

JO - Evidence-Based Dentistry

JF - Evidence-Based Dentistry

SN - 1462-0049

IS - 3

ER -