Abstract
Data are presented indicating that the adhesion of Chinese hamster ovary cells (CHO) to films of denatured type I collagen occurs by a fibronectin-dependent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism. Data are also presented indicating that fibronectin promotes the migration of CHO cells on native type I collagen fibres.
Original language | English |
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Pages (from-to) | 299-310 |
Number of pages | 12 |
Journal | Journal of Cell Science |
Volume | 49 |
Publication status | Published - Jun 1981 |
Keywords
- Animals
- Cell Adhesion/drug effects
- Cell Division/drug effects
- Cell Line
- Cell Movement/drug effects
- Collagen
- Cricetinae
- Cricetulus
- Female
- Fibronectins/pharmacology
- Ovary/cytology