The effects of fibronectin on the adhesion and migration of chinese hamster ovary cells on collagen substrata

S L Schor; A M Schor; G W Bazill

The effects of fibronectin on the adhesion and migration of chinese hamster ovary cells on collagen substrata

S L Schor
, A M Schor
, G W Bazill

Research output: Contribution to journal › Article › peer-review

Abstract

Data are presented indicating that the adhesion of Chinese hamster ovary cells (CHO) to films of denatured type I collagen occurs by a fibronectin-dependent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism. Data are also presented indicating that fibronectin promotes the migration of CHO cells on native type I collagen fibres.

Original language	English
Pages (from-to)	299-310
Number of pages	12
Journal	Journal of Cell Science
Volume	49
Publication status	Published - Jun 1981

Keywords

Animals
Cell Adhesion/drug effects
Cell Division/drug effects
Cell Line
Cell Movement/drug effects
Collagen
Cricetinae
Cricetulus
Female
Fibronectins/pharmacology
Ovary/cytology

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https://jcs.biologists.org/content/49/1/299.long

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title = "The effects of fibronectin on the adhesion and migration of chinese hamster ovary cells on collagen substrata",

abstract = "Data are presented indicating that the adhesion of Chinese hamster ovary cells (CHO) to films of denatured type I collagen occurs by a fibronectin-dependent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism. Data are also presented indicating that fibronectin promotes the migration of CHO cells on native type I collagen fibres.",

keywords = "Animals, Cell Adhesion/drug effects, Cell Division/drug effects, Cell Line, Cell Movement/drug effects, Collagen, Cricetinae, Cricetulus, Female, Fibronectins/pharmacology, Ovary/cytology",

author = "Schor, \{S L\} and Schor, \{A M\} and Bazill, \{G W\}",

year = "1981",

month = jun,

language = "English",

volume = "49",

pages = "299--310",

journal = "Journal of Cell Science",

issn = "0021-9533",

publisher = "Company of Biologists Ltd",

}

TY - JOUR

T1 - The effects of fibronectin on the adhesion and migration of chinese hamster ovary cells on collagen substrata

AU - Schor, S L

AU - Schor, A M

AU - Bazill, G W

PY - 1981/6

Y1 - 1981/6

N2 - Data are presented indicating that the adhesion of Chinese hamster ovary cells (CHO) to films of denatured type I collagen occurs by a fibronectin-dependent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism. Data are also presented indicating that fibronectin promotes the migration of CHO cells on native type I collagen fibres.

AB - Data are presented indicating that the adhesion of Chinese hamster ovary cells (CHO) to films of denatured type I collagen occurs by a fibronectin-dependent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism, whereas the adhesion of these cells to 3-dimensional gels of native type I collagen fibres may occur by either a rapid, fibronectin-dependent mechanism or by a slower, fibronectin-independent mechanism. Data are also presented indicating that fibronectin promotes the migration of CHO cells on native type I collagen fibres.

KW - Animals

KW - Cell Adhesion/drug effects

KW - Cell Division/drug effects

KW - Cell Line

KW - Cell Movement/drug effects

KW - Collagen

KW - Cricetinae

KW - Cricetulus

KW - Female

KW - Fibronectins/pharmacology

KW - Ovary/cytology

M3 - Article

C2 - 7198128

SN - 0021-9533

VL - 49

SP - 299

EP - 310

JO - Journal of Cell Science

JF - Journal of Cell Science

ER -

The effects of fibronectin on the adhesion and migration of chinese hamster ovary cells on collagen substrata

Abstract

Keywords

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