TY - JOUR
T1 - The ELF Honest Data Broker
T2 - Informatics enabling public-private collaboration in a precompetitive arena
AU - Paillard, Guillaume
AU - Cochrane, Philip
AU - Jones, Philip S.
AU - Van Hoorn, Willem P.
AU - Caracoti, Andrei
AU - Van Vlijmen, Herman
AU - Pannifer, Andrew D.
N1 - We acknowledge the input and support of the seven EFPIA companies: AstraZeneca, Bayer, Janssen Pharmaceuticals, Lundbeck, Sanofi, Merck-Serono and UCB. This project has received support from the Innovative Medicines Initiative Joint Undertaking under grant agreement no. 115489, resources of which include financial contribution from the European Union's Seventh Framework Programme (FP7/2007-2013) and EFPIA companies’ in-kind contribution.
PY - 2016/1/1
Y1 - 2016/1/1
N2 - New precompetitive ways of working in the pharmaceutical industry are driving the development of new informatics systems to enable their execution and management. The European Lead Factory (ELF) is a precompetitive, 30-partner collaboration between academic groups, small-medium enterprises and pharmaceutical companies created to discover small molecule hits against novel biological targets. A unique HTS screening and triage workflow has been developed to balance the intellectual property and scientific requirements of all the partners. Here, we describe the ELF Honest Data Broker, a cloud-based informatics system providing the scientific triage tools, fine-grained permissions and management tools required to implement the workflow.
AB - New precompetitive ways of working in the pharmaceutical industry are driving the development of new informatics systems to enable their execution and management. The European Lead Factory (ELF) is a precompetitive, 30-partner collaboration between academic groups, small-medium enterprises and pharmaceutical companies created to discover small molecule hits against novel biological targets. A unique HTS screening and triage workflow has been developed to balance the intellectual property and scientific requirements of all the partners. Here, we describe the ELF Honest Data Broker, a cloud-based informatics system providing the scientific triage tools, fine-grained permissions and management tools required to implement the workflow.
UR - http://www.scopus.com/inward/record.url?scp=84960205395&partnerID=8YFLogxK
U2 - 10.1016/j.drudis.2015.11.005
DO - 10.1016/j.drudis.2015.11.005
M3 - Review article
C2 - 26608890
AN - SCOPUS:84960205395
SN - 1359-6446
VL - 21
SP - 97
EP - 102
JO - Drug Discovery Today
JF - Drug Discovery Today
IS - 1
ER -
