Projects per year
Bacteria export proteins across membranes using a range of transport machineries. Type VII secretion systems (T7SSs), originally described in mycobacteria, are now known to be widespread across diverse bacterial phyla. Recent studies have characterized secretion components and mechanisms of type VII secretion in pathogenic and environmental bacteria. A variety of functions have been attributed to T7SS substrates, including interactions with eukaryotes and with other bacteria. Here, we evaluate the growing body of knowledge on T7SSs, with focus on the nonmycobacterial systems, reviewing their phylogenetic distribution, structure and function in diverse settings.
|Number of pages||13|
|Journal||Trends in Microbiology|
|Early online date||25 Nov 2016|
|Publication status||Published - Mar 2017|
- Type VII secretion
FingerprintDive into the research topics of 'The Enigmatic Esx Proteins: Looking Beyond Mycobacteria'. Together they form a unique fingerprint.
- 1 Finished
Characterisation of the Ess Protein Secretion System of Staphylococcus Aureus a Key Virulence Factor
Hunter, B. & Palmer, T.
1/04/15 → 31/05/18