TY - CHAP
T1 - The epidemiology of transplant-associated keratinocyte cancers in different geographical regions
AU - Proby, Charlotte M.
AU - Wisgerhof, Hermina C.
AU - Casabonne, Delphine
AU - Green, Adele C.
AU - Harwood, Catherine A.
AU - Bouwes Bavinck, Jan N.
PY - 2009/1/1
Y1 - 2009/1/1
N2 - There are believed to be more than 1 million individuals worldwide currently with an organ allograft [1], and a further steep increase in numbers is expected in the next decade. The life-enhancing benefits of organ transplantation are undisputed, but come at a cost. Complications from graft-preserving iatrogenic immunosuppression include a significantly increased risk of malignancy. More than 40 primary malignant neoplasms were reported in the first 4,000 patients to undergo renal transplantation [2], and this early observation has been consistently supported by subsequent studies [3-7].
AB - There are believed to be more than 1 million individuals worldwide currently with an organ allograft [1], and a further steep increase in numbers is expected in the next decade. The life-enhancing benefits of organ transplantation are undisputed, but come at a cost. Complications from graft-preserving iatrogenic immunosuppression include a significantly increased risk of malignancy. More than 40 primary malignant neoplasms were reported in the first 4,000 patients to undergo renal transplantation [2], and this early observation has been consistently supported by subsequent studies [3-7].
UR - http://www.scopus.com/inward/record.url?scp=77953682654&partnerID=8YFLogxK
U2 - 10.1007/978-0-387-78574-5_7
DO - 10.1007/978-0-387-78574-5_7
M3 - Other chapter contribution
C2 - 19415194
AN - SCOPUS:77953682654
VL - 146
SP - 75
EP - 95
BT - Cancer Treatment and Research
ER -
