Abstract
Background: The ERA-EDTA Registry collects data on kidney replacement therapy (KRT) via national and regional renal registries in Europe and countries bordering the Mediterranean Sea. This article summarizes the 2018 ERA-EDTA Registry Annual Report, and describes the epidemiology of KRT for kidney failure in 34 countries.
Methods: Individual patient data on patients undergoing KRT in 2018 was provided by 34 national or regional renal registries and aggregated data by 17 registries. The incidence and prevalence of KRT, the kidney transplantation activity and the survival probabilities of these patients were calculated.
Results: In 2018, the ERA-EDTA Registry covered a general population of 636 million people. Overall, the incidence of KRT for kidney failure was 129 per million population (pmp), 62% of patients were men, 51% were ≥65 years of age and 20% had diabetes mellitus as cause of kidney failure. Treatment modality at the onset of KRT was haemodialysis for 84%, peritoneal dialysis for 11% and pre-emptive kidney transplantation for 5% of patients. On 31 December 2018, the prevalence of KRT was 897 pmp, with 57% of patients on haemodialysis, 5% on peritoneal dialysis, and 38% living with a kidney transplant. The transplant rate in 2018 was 35 pmp: 68% received a kidney from a deceased donor, 30% from a living donor, and for 2% the donor source was unknown. For patients commencing dialysis during 2009-2013, the unadjusted 5-year survival probability was 42.6%. For patients receiving a kidney transplant within this period the unadjusted 5-year survival probability was 86.6% for recipients of deceased donor grafts, and 93.9% for recipients of living donor graft
Methods: Individual patient data on patients undergoing KRT in 2018 was provided by 34 national or regional renal registries and aggregated data by 17 registries. The incidence and prevalence of KRT, the kidney transplantation activity and the survival probabilities of these patients were calculated.
Results: In 2018, the ERA-EDTA Registry covered a general population of 636 million people. Overall, the incidence of KRT for kidney failure was 129 per million population (pmp), 62% of patients were men, 51% were ≥65 years of age and 20% had diabetes mellitus as cause of kidney failure. Treatment modality at the onset of KRT was haemodialysis for 84%, peritoneal dialysis for 11% and pre-emptive kidney transplantation for 5% of patients. On 31 December 2018, the prevalence of KRT was 897 pmp, with 57% of patients on haemodialysis, 5% on peritoneal dialysis, and 38% living with a kidney transplant. The transplant rate in 2018 was 35 pmp: 68% received a kidney from a deceased donor, 30% from a living donor, and for 2% the donor source was unknown. For patients commencing dialysis during 2009-2013, the unadjusted 5-year survival probability was 42.6%. For patients receiving a kidney transplant within this period the unadjusted 5-year survival probability was 86.6% for recipients of deceased donor grafts, and 93.9% for recipients of living donor graft
| Original language | English |
|---|---|
| Pages (from-to) | 107-123 |
| Number of pages | 17 |
| Journal | Clinical Kidney Journal |
| Volume | 14 |
| Issue number | 1 |
| Early online date | 24 Dec 2020 |
| DOIs | |
| Publication status | Published - Jan 2021 |
Keywords
- dialysis
- epidemiology
- kidney failure
- kidney transplantation
- survival analysis
