The expression of 3-fucosylated-N-acetyl lactosamine carbohydrate determinants in renal tumours

S. Fleming; G. Brown

doi:10.1111/j.1365-2559.1987.tb02620.x

The expression of 3-fucosylated-N-acetyl lactosamine carbohydrate determinants in renal tumours

S. Fleming, G. Brown

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7 Citations (Scopus)

Abstract

The distribution in renal tumours of 3-fucosyl-N-acetyl lactosamine has been studied by using the monoclonal antibodies AGF 4.36 and AGF 4.48 and immunoperoxidase methods on tissue sections. Seven of 19 nephroblastomas and 12 of 30 renal cell carcinomas contained the epitope. In nephroblastomas the epitope was found on the terminals of type B tubules in six cases and in one case on the type A or neoplastic tubules. In renal carcinoma the antigen was found on the surface of tumour cells. The results suggest that in kidneys bearing nephroblastomas ureteric bud elements may grow into the tumour from the adjacent kidney.

Original language	English
Pages (from-to)	171-182
Number of pages	12
Journal	Histopathology
Volume	11
Issue number	2
DOIs	https://doi.org/10.1111/j.1365-2559.1987.tb02620.x
Publication status	Published - 1987

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title = "The expression of 3-fucosylated-N-acetyl lactosamine carbohydrate determinants in renal tumours",

abstract = "The distribution in renal tumours of 3-fucosyl-N-acetyl lactosamine has been studied by using the monoclonal antibodies AGF 4.36 and AGF 4.48 and immunoperoxidase methods on tissue sections. Seven of 19 nephroblastomas and 12 of 30 renal cell carcinomas contained the epitope. In nephroblastomas the epitope was found on the terminals of type B tubules in six cases and in one case on the type A or neoplastic tubules. In renal carcinoma the antigen was found on the surface of tumour cells. The results suggest that in kidneys bearing nephroblastomas ureteric bud elements may grow into the tumour from the adjacent kidney.",

author = "S. Fleming and G. Brown",

year = "1987",

doi = "10.1111/j.1365-2559.1987.tb02620.x",

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AU - Fleming, S.

AU - Brown, G.

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AB - The distribution in renal tumours of 3-fucosyl-N-acetyl lactosamine has been studied by using the monoclonal antibodies AGF 4.36 and AGF 4.48 and immunoperoxidase methods on tissue sections. Seven of 19 nephroblastomas and 12 of 30 renal cell carcinomas contained the epitope. In nephroblastomas the epitope was found on the terminals of type B tubules in six cases and in one case on the type A or neoplastic tubules. In renal carcinoma the antigen was found on the surface of tumour cells. The results suggest that in kidneys bearing nephroblastomas ureteric bud elements may grow into the tumour from the adjacent kidney.

U2 - 10.1111/j.1365-2559.1987.tb02620.x

DO - 10.1111/j.1365-2559.1987.tb02620.x

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SP - 171

EP - 182

JO - Histopathology

JF - Histopathology

IS - 2

ER -

The expression of 3-fucosylated-N-acetyl lactosamine carbohydrate determinants in renal tumours

Abstract

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