The Face of Chromatin Variants

Andrew Flaus; Tom Owen-Hughes

doi:10.1016/j.cell.2019.08.024

The Face of Chromatin Variants

Andrew Flaus, Tom Owen-Hughes (Lead / Corresponding author)

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Abstract

A developmental program affecting human face shape is shown by Greenberg et al. (2019) to hinge on the ability to distinguish a single methyl group between two histone variant isoforms and the action of the chromatin-remodeling enzyme SRCAP. This challenges researchers to link atomic structure to a morphological defect.

Original language	English
Pages (from-to)	1284-1286
Number of pages	3
Journal	Cell
Volume	178
Issue number	6
Early online date	5 Sept 2019
DOIs	https://doi.org/10.1016/j.cell.2019.08.024
Publication status	Published - 5 Sept 2019

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology

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10.1016/j.cell.2019.08.024Licence: Elsevier User Licence

Author Accepted ManuscriptAccepted author manuscript, 220 KBLicence: CC BY-NC-ND

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title = "The Face of Chromatin Variants",

abstract = "A developmental program affecting human face shape is shown by Greenberg et al. (2019) to hinge on the ability to distinguish a single methyl group between two histone variant isoforms and the action of the chromatin-remodeling enzyme SRCAP. This challenges researchers to link atomic structure to a morphological defect.",

author = "Andrew Flaus and Tom Owen-Hughes",

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The Face of Chromatin Variants

Abstract

ASJC Scopus subject areas

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Structure and Function of Chromatin Remodelling ATPases and their Dysfunction in Human Disease

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The Face of Chromatin Variants

Abstract

ASJC Scopus subject areas

Access to Document

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Structure and Function of Chromatin Remodelling ATPases and their Dysfunction in Human Disease

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