The Face of Chromatin Variants

Andrew Flaus; Tom Owen-Hughes

doi:10.1016/j.cell.2019.08.024

The Face of Chromatin Variants

Andrew Flaus
, Tom Owen-Hughes (Lead / Corresponding author)

Research output: Contribution to journal › Article › peer-review

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Abstract

A developmental program affecting human face shape is shown by Greenberg et al. (2019) to hinge on the ability to distinguish a single methyl group between two histone variant isoforms and the action of the chromatin-remodeling enzyme SRCAP. This challenges researchers to link atomic structure to a morphological defect.

Original language	English
Pages (from-to)	1284-1286
Number of pages	3
Journal	Cell
Volume	178
Issue number	6
Early online date	5 Sept 2019
DOIs	https://doi.org/10.1016/j.cell.2019.08.024
Publication status	Published - 5 Sept 2019

ASJC Scopus subject areas

General Biochemistry,Genetics and Molecular Biology

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10.1016/j.cell.2019.08.024Licence: Elsevier User Licence

Author Accepted ManuscriptAccepted author manuscript, 220 KBLicence: CC BY-NC-ND

Cite this

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title = "The Face of Chromatin Variants",

abstract = "A developmental program affecting human face shape is shown by Greenberg et al. (2019) to hinge on the ability to distinguish a single methyl group between two histone variant isoforms and the action of the chromatin-remodeling enzyme SRCAP. This challenges researchers to link atomic structure to a morphological defect.",

author = "Andrew Flaus and Tom Owen-Hughes",

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AB - A developmental program affecting human face shape is shown by Greenberg et al. (2019) to hinge on the ability to distinguish a single methyl group between two histone variant isoforms and the action of the chromatin-remodeling enzyme SRCAP. This challenges researchers to link atomic structure to a morphological defect.

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The Face of Chromatin Variants

Abstract

ASJC Scopus subject areas

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Structure and Function of Chromatin Remodelling ATPases and their Dysfunction in Human Disease

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The Face of Chromatin Variants

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Projects

Structure and Function of Chromatin Remodelling ATPases and their Dysfunction in Human Disease

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