The first direct preparation of chiral functionalised ketones and their synthetic uses

José Barluenga, Beatriz Baragaña, Alejandro Alonso, José M. Concellón

Research output: Contribution to journalArticlepeer-review

61 Citations (Scopus)

Abstract

Almost enantiomerically pure halogenated α-hydroxy and α-amino ketones can be prepared from O-protected lactates and tribenzylated alanine, respectively; whilst amino ketones 3g have also been transformed into the amino epoxide 7 with high diastereoselectivity.

Original languageEnglish
Pages (from-to)969-970
Number of pages2
JournalJournal of the Chemical Society, Chemical Communications
Issue number8
DOIs
Publication statusPublished - 1994

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