Almost enantiomerically pure halogenated α-hydroxy and α-amino ketones can be prepared from O-protected lactates and tribenzylated alanine, respectively; whilst amino ketones 3g have also been transformed into the amino epoxide 7 with high diastereoselectivity.
|Number of pages
|Journal of the Chemical Society, Chemical Communications
|Published - 1994
ASJC Scopus subject areas
- Molecular Medicine