The Guanidine Riboswitch-A Poor Orphan No Longer

David M. J. Lilley (Lead / Corresponding author)

Research output: Contribution to journal › Review article

1 Citation (Scopus)

Abstract

Riboswitches are widespread in the bacterial kingdom, where they regulate gene expression in response to different small molecules and ions. However, some remain orphans with no known endogenous ligand. Three recently published papers (Battaglia et al., 2017; Nelson et al., 2017; and Reiss et al., 2017) de-orphanize a widespread ykkC element, showing that it responds to guanidine and elaborating on how that response is mediated.

Original languageEnglish
Pages (from-to)130-131
Number of pages2
JournalCell Chemical Biology
Volume24
Issue number2
DOIs
Publication statusPublished - 16 Feb 2017

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Riboswitch
Guanidine
Gene expression
Ions
Ligands
Gene Expression
Molecules

Keywords

  • Journal article

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Lilley, David M. J. / The Guanidine Riboswitch-A Poor Orphan No Longer. In: Cell Chemical Biology. 2017 ; Vol. 24, No. 2. pp. 130-131.
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Lilley, DMJ 2017, 'The Guanidine Riboswitch-A Poor Orphan No Longer', Cell Chemical Biology, vol. 24, no. 2, pp. 130-131. https://doi.org/10.1016/j.chembiol.2017.01.010

The Guanidine Riboswitch-A Poor Orphan No Longer. / Lilley, David M. J. (Lead / Corresponding author).

In: Cell Chemical Biology, Vol. 24, No. 2, 16.02.2017, p. 130-131.

Research output: Contribution to journal › Review article

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T1 - The Guanidine Riboswitch-A Poor Orphan No Longer

AU - Lilley, David M. J.

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N2 - Riboswitches are widespread in the bacterial kingdom, where they regulate gene expression in response to different small molecules and ions. However, some remain orphans with no known endogenous ligand. Three recently published papers (Battaglia et al., 2017; Nelson et al., 2017; and Reiss et al., 2017) de-orphanize a widespread ykkC element, showing that it responds to guanidine and elaborating on how that response is mediated.

AB - Riboswitches are widespread in the bacterial kingdom, where they regulate gene expression in response to different small molecules and ions. However, some remain orphans with no known endogenous ligand. Three recently published papers (Battaglia et al., 2017; Nelson et al., 2017; and Reiss et al., 2017) de-orphanize a widespread ykkC element, showing that it responds to guanidine and elaborating on how that response is mediated.

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DO - 10.1016/j.chembiol.2017.01.010

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JF - Cell Chemical Biology

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Lilley DMJ. The Guanidine Riboswitch-A Poor Orphan No Longer. Cell Chemical Biology. 2017 Feb 16;24(2):130-131. https://doi.org/10.1016/j.chembiol.2017.01.010

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