The hypo-osmotic swelling test and the sperm mucus penetration test in determining fertilization of the human oocyte

C. L. Barratt (Lead / Corresponding author), J. C. Osborn, P. E. Harrison, N. Monks, B. C. Dunphy, E. A. Lenton, I. D. Cooke

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

The usefulness of the hypo-osmotic swelling (HOS) test and the sperm mucus penetration (SMP) test as sperm function tests for in-vitro fertilization was analysed in 56 couples. Using logistic regression analysis only the SMP test was independently related to fertilization (P = 0.004), no false negative results were obtained, i.e. no fertilization if sperm from the ejaculate failed to penetrate mucus. The HOS test was of no predictive value. The results justify a further examination of the SMP test in other IVF centres.

Original languageEnglish
Pages (from-to)430-4
Number of pages5
JournalHuman Reproduction
Volume4
Issue number4
DOIs
Publication statusPublished - 1 May 1989

Keywords

  • Cervix Mucus
  • Female
  • Fertilization in Vitro
  • Humans
  • Male
  • Oocytes/physiology
  • Osmolar Concentration
  • Osmotic Pressure
  • Spermatozoa/physiology

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