The hypo-osmotic swelling test and the sperm mucus penetration test in determining fertilization of the human oocyte

TY - JOUR

T1 - The hypo-osmotic swelling test and the sperm mucus penetration test in determining fertilization of the human oocyte

AU - Barratt, C. L.

AU - Osborn, J. C.

AU - Harrison, P. E.

AU - Monks, N.

AU - Dunphy, B. C.

AU - Lenton, E. A.

AU - Cooke, I. D.

PY - 1989/5/1

Y1 - 1989/5/1

N2 - The usefulness of the hypo-osmotic swelling (HOS) test and the sperm mucus penetration (SMP) test as sperm function tests for in-vitro fertilization was analysed in 56 couples. Using logistic regression analysis only the SMP test was independently related to fertilization (P = 0.004), no false negative results were obtained, i.e. no fertilization if sperm from the ejaculate failed to penetrate mucus. The HOS test was of no predictive value. The results justify a further examination of the SMP test in other IVF centres.

AB - The usefulness of the hypo-osmotic swelling (HOS) test and the sperm mucus penetration (SMP) test as sperm function tests for in-vitro fertilization was analysed in 56 couples. Using logistic regression analysis only the SMP test was independently related to fertilization (P = 0.004), no false negative results were obtained, i.e. no fertilization if sperm from the ejaculate failed to penetrate mucus. The HOS test was of no predictive value. The results justify a further examination of the SMP test in other IVF centres.

KW - Cervix Mucus

KW - Female

KW - Fertilization in Vitro

KW - Humans

KW - Male

KW - Oocytes/physiology

KW - Osmolar Concentration

KW - Osmotic Pressure

KW - Spermatozoa/physiology

U2 - 10.1093/oxfordjournals.humrep.a136922

DO - 10.1093/oxfordjournals.humrep.a136922

M3 - Article

C2 - 2745673

SN - 0268-1161

VL - 4

SP - 430

EP - 434

JO - Human Reproduction

JF - Human Reproduction

IS - 4

ER -